Motivation levels vary across individuals, yet the underlying mechanisms driving these differences remain elusive. The dorsomedial prefrontal cortex/dorsal anterior cingulate cortex (dmPFC/dACC) and the anterior insula (aIns) play crucial roles in effort-b ...
BackgroundThe imbalance of glutamate (Glu) and gamma-aminobutyric acid (GABA) neurotransmitter system plays a crucial role in the pathogenesis of Alzheimer's disease (AD). Riluzole is a Glu modulator originally approved for amyotrophic lateral sclerosis th ...
Colorectal cancer (CRC) still remains the leading cause of cancer death worldwide. This study aimed to profile the metabolic differences of colorectal cancer tissues (CCT) at different stages and sites, as compared with their distant noncancerous tissues ( ...
Background: Sleep deprivation causes hippocampal injury, manifesting as neuronal damage and learning-memory impairment. These negative effects may be associated with disturbance of hippocampal glutamate and water homeostasis, which induces excessive neuron ...
Purpose: Phosphorus MRS (31P MRS) enables noninvasive assessment of energy metabolism, yet its application is hindered by sensitivity limitations. To overcome this, often high magnetic fields are used, leading to challenges such as spatial (Formula present ...
Magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI), are non-invasive techniques used to quantify biochemical compounds in tissue, such as choline, creatine, glutamate, glutamine, γ-aminobutyric acid, N-acetylaspartate ...
Whole-brain proton magnetic resonance spectroscopic imaging (H-1-MRSI) is a non-invasive technique for assessing neurochemical distribution in the brain, offering valuable insights into brain functions and neural diseases. It greatly benefits from the impr ...
Background and purpose: This study aims to evaluate the neurochemical characteristics of pathological tissues by 1H magnetic resonance spectroscopy (MRS) in patient with pharmaco-resistant focal epilepsy at 7 T. Methods: Thirteen patients with drug-resista ...
Objective: This study evaluates the performance of a twisted pair transmission line coil as a transceive element for 7 T MRI in terms of physical flexibility, robustness to shape deformations, and interelement decoupling. Methods: Each coil element was cre ...
