Anna Katherine Renfrew

Cette personne n’est plus à l’EPFL

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (18)

Ruthenium(II) Arene Compounds as Versatile Anticancer Agents

Anna Katherine Renfrew

Ruthenium-based compounds are an attractive alternative to clinically used platinum drugs due to several features including a wide range of accessible oxidation states, varied synthetic chemistry and typically lower general toxicities. One series of ruthen ...

2009

Tuning the efficacy of ruthenium(II)-arene (RAPTA) antitumour compounds with fluorinated arene ligands

Paul Joseph Dyson, Rosario Scopelliti, Ursula Röthlisberger, Anna Katherine Renfrew, Andrew Douglas Phillips, Enrico Marko Tapavicza

A series of compounds of general formula [Ru(eta(6)-fluoroarene)(pta)Cl-2] (fluoroarene = C6H5F, C6H5CF3, and 1,4-C6H4CH3F; pta = 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane) have been prepared and characterized spectroscopically. Additionally, X-ray dif ...

American Chemical Society2009

Synthesis, Molecular Structure, and Anticancer Activity of Cationic Arene Ruthenium Metallarectangles

Paul Joseph Dyson, Anna Katherine Renfrew

Cationic arene ruthenium-based tetranuclear complexes comprising rectangular structures have been obtained from the dinuclear arene ruthenium complexes [Ru2(arene)2(OO.intrsec.OO)2Cl2] (arene = p-cymene, hexamethylbenzene; OO.intrsec.OO = 2,5-dihydroxy-1,4 ...

American Chemical Society2009

Arene-ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(η6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(η6-arene)(NC3H3N(CH2)2O2C-C5H4FeC5H5)Cl2]

Paul Joseph Dyson, Anna Katherine Renfrew

Pyridylferrocene and imidazolylferrocene arene-Ru complexes [Ru(η6-arene)(L)Cl2] where L = NC5H4CH2NHOCC5H4FeC5H5, arene = p-iPrC6H4Me (1) or C6Me6 (2); L = NC3H3N(CH2)2O2CC5H4FeC5H5, arene = p-iPrC6H4Me (3) or C6Me6 (4), and diruthenium-arene complexes [R ...

2009

Anticancer activity of multinuclear arene ruthenium complexes coordinated to dendritic polypyridyl scaffolds

Paul Joseph Dyson, Anna Katherine Renfrew

The rational development of multinuclear arene ruthenium complexes (arene = p-cymene, hexamethylbenzene) from generation 1 (G1) and generation 2 (G2) of 4-iminopyridyl based poly(propyleneimine) dendrimer scaffolds of the type, DAB-(NH2)n (n = 4 or 8, DAB ...

Elsevier2009

Influence of the diketonato ligand on the cytotoxicities of [Ru(.eta.6-p-cymene)(R2acac)(PTA)]+ complexes (PTA = 1,3,5-triaza-7-phosphaadamantane)

Paul Joseph Dyson, Rosario Scopelliti, Anna Katherine Renfrew

A series of compds. of general formula [Ru(.eta.6-p-cymene) (R2acac)(PTA)][X] (R2acac = Me2acac, tBu2acac, Ph2acac, Me2acac-Cl; PTA = 1,3,5-triaza-7-phosphaadamantane; X = BPh4, BF4), and the precursor to the Me2acac-Cl deriv. [Ru(.eta.6-p-cymene)(Me2acac- ...

2008

Water-soluble arene ruthenium complexes containing pyridinethiolato ligands: Synthesis, molecular structure, redox properties and anticancer activity of the cations [(η6-arene)Ru(p-SC5H4NH)3]2+

Paul Joseph Dyson, Anna Katherine Renfrew

The cationic complexes [(η6-arene)Ru(SC5H4NH)3]2+, arene being C6H6 (1), MeC6H5 (2), p-iPrC6H4Me (3) or C6Me6 (4), have been synthesized from the reaction of 4-pyridinethiol with the corresponding precursor (η6-arene)2Ru2(μ2-Cl)2Cl2 and isolated as the chl ...

2008

The "complex-in-a-complex" cations [(acac)2M.cntnd.Ru6-(p-iPrC6H4Me)6(tpt)2(dhbq)3]6+: a trojan horse for cancer cells

Paul Joseph Dyson, Anna Katherine Renfrew

The cytotoxicities of the large cationic arene-ruthenium prismatic cage [Ru6(p-iPrC6H4Me)6(tpt)2(dhbq)3]6+ (tpt = 2,4,6-tris(pyridin-4-yl)-1,3,5-triazine, dhbq = 2,5-dihydroxy-1,4-benzoquinolato; 16+), and its "complex-in-a-complex" derivs. [(acac)2M-1]6+ ...

Wiley-VCH Verlag GmbH2008

Page 2 sur 2

Influence of the diketonato ligand on the cytotoxicities of [Ru(.eta.6-p-cymene)(R2acac)(PTA)]+ complexes (PTA = 1,3,5-triaza-7-phosphaadamantane)

Paul Joseph Dyson, Rosario Scopelliti, Anna Katherine Renfrew

2008

The "complex-in-a-complex" cations [(acac)2M.cntnd.Ru6-(p-iPrC6H4Me)6(tpt)2(dhbq)3]6+: a trojan horse for cancer cells

Paul Joseph Dyson, Anna Katherine Renfrew

Wiley-VCH Verlag GmbH2008

Arene-ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(η6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(η6-arene)(NC3H3N(CH2)2O2C-C5H4FeC5H5)Cl2]

Paul Joseph Dyson, Anna Katherine Renfrew

2009

Anticancer activity of multinuclear arene ruthenium complexes coordinated to dendritic polypyridyl scaffolds

Paul Joseph Dyson, Anna Katherine Renfrew

Elsevier2009

Water-soluble arene ruthenium complexes containing pyridinethiolato ligands: Synthesis, molecular structure, redox properties and anticancer activity of the cations [(η6-arene)Ru(p-SC5H4NH)3]2+

Paul Joseph Dyson, Anna Katherine Renfrew

2008