Publications de James Brandon Dixon

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium

Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, James Brandon Dixon, Dimana Miteva

RATIONALE: Lymphatic transport of peripheral interstitial fluid and dendritic cells (DCs) is important for both adaptive immunity and maintenance of tolerance to self-antigens. Lymphatic drainage can change rapidly and dramatically on tissue injury or infl ...

American Heart Association2010

A multichamber fluidic device for 3D cultures under interstitial flow with live imaging: Development, characterization, and applications

Melody Swartz, Jan Overney, James Brandon Dixon, Adrian Chung-Kai Shieh, Carmen Bonvin

Interstitial flow is an important biophysical cue that can affect capillary morphogenesis, tumor cell migration, and fibroblast remodeling of the extracellular matrix, among others. Current models that incorporate interstitial flow and that are suitable fo ...

Wiley-Blackwell2010

A tissue-engineered model of the intestinal lacteal for evaluating lipid transport by lymphatics

Melody Swartz, Sandeep Raghunathan, James Brandon Dixon

Lacteals are the entry point of all dietary lipids into the circulation, yet little is known about the active regulation of lipid uptake by these lymphatic vessels, and there lacks in vitro models to study the lacteal-enterocyte interface. We describe an i ...

Wiley-Blackwell2009

An in vitro model of the intestinal lymphatics for transport studies of lipid and drug carriers

Melody Swartz, Sandeep Raghunathan, James Brandon Dixon

2009

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium: An early indicator of injury and inflammation?

Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, James Brandon Dixon, Dimana Miteva

Karger2009