Publications de Thomas Jean Victor Marie Lanvin

Subsurface ablation of tissue by ultrafast laser

Laser-induced optical breakdown (LIOB) is a multiphoton process which can be used for selective removal of material. It revolves around the creation of a plasma in the focal volume of a beam, and requires very high peak intensities in the order of the GW.c ...

EPFL2017

Ultrafast laser ablation for targeted atherosclerotic plaque removal

Laurent Descloux, Demetri Psaltis, Donald Benjaman Conkey, Thomas Jean Victor Marie Lanvin

Coronary artery disease, the main cause of heart disease, develops as immune cells and lipids accumulate into plaques within the coronary arterial wall. As a plaque grows, the tissue layer (fibrous cap) separating it from the blood flow becomes thinner and ...

Spie-Int Soc Optical Engineering2015

Subsurface ablation of atherosclerotic plaque using ultrafast laser pulses

Demetri Psaltis, Donald Benjaman Conkey, Thomas Jean Victor Marie Lanvin

We perform subsurface ablation of atherosclerotic plaque using ultrafast pulses. Excised mouse aortas containing atherosclerotic plaque were ablated with ultrafast near-infrared (NIR) laser pulses. Optical coherence tomography (OCT) was used to observe the ...

Optical Soc Amer2015

Ablation device and method for subsurface biological tissue ablation

Demetri Psaltis, Alexandre Goy, Jae-Woo Choi, Thomas Jean Victor Marie Lanvin

The present invention relates to a subsurface laser-induced optical breakdown (LIOB) ablation system including an optical source for providing optical pulses and an optical waveguide for guiding the optical pulses to a subsurface target biological tissue s ...

2015

Catheter for sub-surface ablation in biological tissue

Demetri Psaltis, Jae-Woo Choi, Donald Benjaman Conkey, Thomas Jean Victor Marie Lanvin

The present invention concerns a subsurface laser-induced optical breakdown (LIOB) catheter including a probe assembly for providing at least one optical pulse to a subsurface target biological tissue site; and a waveguide for guiding the at least one opti ...

2015

Imaging with second-harmonic radiation probes in living tissue

Demetri Psaltis, Ye Pu, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Thomas Jean Victor Marie Lanvin

We demonstrate that second-harmonic radiation imaging probes are efficient biomarkers for imaging in living tissue. We show that 100 nm and 300 nm BaTiO3 nanoparticles used as contrast markers could be detected through 50 mu m and 120 mu m of mouse tail ti ...

2011