Publications de Andrea Corsinotti

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

Didier Trono, Andrea Corsinotti, Bart Deplancke, Sebastian Martin Waszak, Sunil Kumar Raghav, Petra Catalina Schwalie, Gilles Udin

Adipose tissue is a key determinant of whole body metabolism and energy homeostasis. Unraveling the regulatory mechanisms underlying adipogenesis is therefore highly relevant from a biomedical perspective. Our current understanding of fat cell differentiat ...

Elife Sciences Publications Ltd2014

Control of mitophagie by microRNAs - A key step of erythropoiesis

Didier Trono, Jiri Vanicek, Isabelle Barde, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Sonia Verp, Andrea Corsinotti, Ray Marcel Marin Florez, Benjamin Rauwel

Edp Sciences S A2014

A KRAB/KAP1-miRNA Cascade Regulates Erythropoiesis Through Stage-Specific Control of Mitophagy

Didier Trono, Jiri Vanicek, Sandra Eloise Kjeldsen, Isabelle Barde, Sonia Verp, Adamantia Kapopoulou, Andrea Corsinotti, Benjamin Rauwel, Ray Marcel Marin Florez

During hematopoiesis, lineage- and stage-specific transcription factors work in concert with chromatin modifiers to direct the differentiation of all blood cells. Here, we explored the role of KRAB-containing zinc finger proteins (KRAB-ZFPs) and their cofa ...

American Association for the Advancement of Science2013

Global and stage specific patterns of krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells

Didier Trono, Bart Deplancke, Adamantia Kapopoulou, Andrea Corsinotti, Michaël Imbeault, Yoann Mouscaz, Carine Delattre-Gubelmann, Helen Mary Rowe

Highly coordinated transcription networks orchestrate the self-renewal of pluripotent stem cell and the earliest steps of mammalian development. KRAB-containing zinc finger proteins represent the largest group of transcription factors encoded by the genome ...

Public Library of Science2013

KRAB/KAP1 Regulation of Embryonic Stem Cell Pluripotent Self-renewal

Andrea Corsinotti

KRAB-ZFPs constitute the largest family of transcription factors (TFs) encoded by the mouse genome and are known to interact with the co-repressor KAP1. KRAB/KAP1-mediated regulation is essential for several development- and ESC- specific functions, in par ...

EPFL2012