Publications de Oleg Vechorkin

Synthesis and electronic properties of a pentafluoroethyl-derivatized nickel pincer complex

The synthesis of a bis(amino)amide nickel pincer complex bearing a perfluoroethyl ligand was effected by reaction of the corresponding nickel chloride complex with cesium fluoride and trimethyl(pentafluoroethyl)silane. Electrochemical experiments revealed ...

Royal Society of Chemistry2012

A Well-Defined Ni Pincer Catalyst for Cross Coupling of Non-Activated Alkyl Halides and Direct C-H Alkylation

Oleg Vechorkin

Carbon-carbon bond forming reactions are among the most important and useful methods for organic synthesis. During the last years, significant progress has been made in this field. Whereas many catalysts were developed for the coupling of aryl, alkenyl, an ...

EPFL2011

Cross coupling of non-activated alkyl halides with alkynyl Grignard reagents catalyzed by a well-defined Ni pincer complex

Rosario Scopelliti, Xile Hu, Aurélien Godinat, Oleg Vechorkin

The nickel pincer complex 1 catalyzes the cross-coupling of the title compounds with remarkable substrate scope and functional group tolerance. A nickel/alkynyl species was isolated and shown to be catalytically competent. THF=tetrahydrofuran, O-TMEDA=bis[ ...

Wiley-VCH Verlag GmbH2011

Pd, Pt, and Ru complexes of a pincer bis(amino)amide ligand

Rosario Scopelliti, Xile Hu, Oleg Vechorkin, Peng Ren, Isuf Salihu

An improved synthesis of pincer ligand bis[(2-dimethylamino)phenyl]amine (MeN2NH) was reported. Reaction of the Li complex of MeN2N with suitable Pd, Pt, and Ru precursors gave the corresponding metal complexes. The structures of the Pd, Pt, and Ru complex ...

Royal Society of Chemistry2011

A Structure-Activity Study of Ni-Catalyzed Alkyl-Alkyl Kumada Coupling. Improved Catalysts for Coupling of Secondary Alkyl Halides

Rosario Scopelliti, Xile Hu, Oleg Vechorkin, Peng Ren, Kim Dimuth Von Allmen

A structure–activity study was carried out for Ni catalyzed alkyl–alkyl Kumada-type cross coupling reactions. A series of new nickel(II) complexes including those with tridentate pincer bis(amino)amide ligands (RN2N) and those with bidentate mixed amino-am ...

2011

Why are (NN2)Ni pincer complexes active for alkyl-alkyl coupling: ß-H elimination is kinetically accessible but thermodynamically uphill

Rosario Scopelliti, Xile Hu, Anne-Clémence Corminboeuf, Oleg Vechorkin, Jan Breitenfeld

Isomerization and olefin exchange experiments show that β-H elimination is kinetically viable but thermodynamically unfavorable in [(MeNN2)Ni-alkyl] complexes. The intermediacy of Ni-hydride species was corroborated by a trapping experiment. The alkyl comp ...

American Chemical Society2010

The Nickel/Copper-Catalyzed Direct Alkylation of Heterocyclic C-H Bonds

Xile Hu, Oleg Vechorkin, Valérie Proust

A general and straightforward protocol for the cross-coupling of non-activated alkyl halides with heterocyclic CH bonds has been developed. The transformation is chemo- and regioselective and many functional groups on both coupling partners are tolerated. ...

Wiley-VCH Verlag GmbH2010

Carbon Dioxide as the C1 Source for Direct C−H Functionalization of Aromatic Heterocycles

Xile Hu, Oleg Vechorkin, Nathalie Hirt

A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocylces such as oxazoles, thiazoles, and oxadiazoles using CO2 as the C1 source. The reactions require no metal catalyst and only Cs2CO3 as the base. A goo ...

American Chemical Society2010

Ni-Catalyzed Cross Coupling of Non-Activated and Functionalized Alkyl Halides with Alkyl Grignard Reagents

Xile Hu, Oleg Vechorkin

The title reaction is realized by using an isolated NiII complex (1). The catalysis tolerates a wide range of important functional groups that are often incompatible with Grignard reagents in cross-coupling reactions. ...

Wiley-VCH Verlag GmbH2009

Nickel Complexes of a Pincer Amidobis(amine) Ligand: Synthesis, Structure, and Activity in Stoichiometric and Catalytic C—C Bond Forming Reactions of Alkyl Halides

Rosario Scopelliti, Xile Hu, Oleg Vechorkin

NiII complexes of the new pincer amidobis(amine) ligand are described. The Ni chloride complex catalyzes Kumada-Corriu-Tamao coupling of unactivated alkyl halides with alkyl Grignard reagents, as well as double C-C coupling of CH2Cl2 with alkyl Grignard re ...

2009