Ayyakkannu Ayyanan

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Publications associées (12)

Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multi-Lineage Differentiation Potential Similar to Mesenchymal Stem Cells

Cathrin Brisken, Ayyakkannu Ayyanan

The epithelial-to-mesenchymal transition (EMT) is an embryonic process that becomes latent in most normal adult tissues. Recently, we have shown that induction of EMT endows breast epithelial cells with stem cell traits. In this report, we have further cha ...

2010

The epithelial-mesenchymal transition generates cells with properties of stem cells

Cathrin Brisken, Ayyakkannu Ayyanan, Jiangyan Yang

The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer invasion and metastasis. We here report that the induction of an EMT in immortalized human mammary epithelial cells (HMLEs) results in the acqu ...