Bart Deplancke

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Publications associées (115)

Optimised set of oligonucleotides for bulk rna barcoding and sequencing

Bart Deplancke, Vincent Roland Julien Gardeux, Riccardo Dainese, Daniel Alpern

The present invention relates generally to the field of nucleic acid sequencing and provides oligonucleotide molecules and barcodes contained therein. These oligonucleotide molecules and barcodes molecules are useful in sequencing to identify and resolve e ...

2023

Diverse cell-specific patterns of alternative polyadenylation in Drosophila

Bart Deplancke, Sandy Lee

Most genes in higher eukaryotes express isoforms with distinct 3' untranslated regions (3' UTRs), generated by alternative polyadenylation (APA). Since 3' UTRs are predominant locations of post-transcriptional regulation, APA can render such programs condi ...

Nature Portfolio2022

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Bart Deplancke, Wouter Saelens

The liver is the largest solid organ in the body, yet it remains incompletely characterized. Here we present a spatial proteogenomic atlas of the healthy and obese human and murine liver combining single-cell CITEseq, single-nuclei sequencing, spatial tran ...

CELL PRESS2022

MarrowQuant 2.0: clinical application of a user-friendly digital hematopathology tool for human bone marrow trephine biopsies

Bart Deplancke, Olaia Maria Naveiras Torres-Quiroga, Rita Sarkis

SPRINGER2022

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

Bart Deplancke, Vincent Roland Julien Gardeux, Fabrice David

For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula Drosophilae, that includes 580,000 nuclei from 15 individually dissected sexed ti ...

American Association for the Advancement of Science2022

Method of preparation of cdna library useful for efficient mrna sequencing and uses thereof

Bart Deplancke, Riccardo Dainese, Daniel Alpern, Mustafa Demir

The invention relates to methods for the preparation of method of preparation of cDNA library based on one or many RNA samples useful for efficient RNA sequencing and uses thereof. The invention further relates to related tools and kits useful in said meth ...

2022

A Label-Free, High-Throughput Phenotypic Screen Of Adipocytic Differentiation Modulators To Accelerate Hematopoietic Recovery

Bart Deplancke, Gerardo Turcatti, Vincent Roland Julien Gardeux, Fabien Kuttler, Damiano Banfi, Aurélien Laurent Jean-Charles Oggier, Vasco Ledebur de Antas de Campos, Pernille Yde Rainer

ELSEVIER SCIENCE INC2022

Mammalian adipogenesis regulator (Areg) cells use retinoic acid signalling to be non- and anti-adipogenic in age-dependent manner

Bart Deplancke, Julie Marie Russeil, Horia Hashimi, Daniel Alpern, Maria Litovchenko, Magda Zachara, Pernille Yde Rainer, Radiana Ferrero

Adipose stem and precursor cells (ASPCs) give rise to adipocytes and determine the composition and plasticity of adipose tissue. Recently, several studies have demonstrated that ASPCs partition into at least three distinct cell subpopulations, including th ...

WILEY2022

Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition

Matthias Lütolf, Bart Deplancke, Esther Amstad, Vincent Roland Julien Gardeux, Julie Marie Russeil, Rita Sarkis, Jörn Pezoldt, Johannes Julius Bues, Antonius Chrisnandy, Riccardo Dainese

DisCo is a deterministic droplet microfluidics tool for single-cell analysis on low cell input samples, which is demonstrated to profile individual intestinal organoids and in vivo-derived small tissues. ...

NATURE PORTFOLIO2022

A Tead1-Apelin axis directs paracrine communication from myogenic to endothelial cells in skeletal muscle

Bart Deplancke, Julie Marie Russeil, Sonia Karaz, Maria Deak, Umji Lee, Benjamin D. Cosgrove

Apelin (Apln) is a myokine that regulates skeletal muscle plasticity and meta-bolism and declines during aging. Through a yeast one-hybrid transcription factor binding screen, we identified the TEA domain transcription factor 1 (Tead1) as a novel regulator ...

CELL PRESS2022

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