Publications de Andrea Negro | EPFL Graph Search

3D Inkjet Printing of Complex, Cell-Laden Hydrogel Structures

Matthias Lütolf, Andrea Negro, Thibaud Cherbuin

Inkjet printing is widely considered a promising strategy to pattern hydrogels and living cells into three-dimensional (3D) constructs that structurally resemble tissues in our body. However, this approach is currently constrained by the limited control ov ...

Nature Research2018

A method for building a structure containing living cells

Matthias Lütolf, Andrea Negro

A composition comprising a first material and a second material, wherein said first material is cross-linkable by a first cross- linking reaction and said second material is cross-linkable by a second cross-linking reaction, wherein said first cross-linkin ...

2016

Method and device for mixing two streams of droplets

Matthias Lütolf, Yoji Tabata, Andrea Negro

The invention relates to a method for mixing a first stream of droplets (1) with at least one second stream of droplets (2) to obtain a third stream of fused droplets (3), by collision and fusion of at least one droplet of the first stream (1) with at leas ...

2016

3D niche microarrays for systems-level analyses of cell fate

Matthias Lütolf, Adrian Ranga, Samy Gobaa, Katarzyna Mosiewicz, Andrea Negro, Yuya Okawa

The behaviour of mammalian cells in a tissue is governed by the three-dimensional (3D) microenvironment and involves a dynamic interplay between biochemical and mechanical signals provided by the extracellular matrix (ECM), cell–cell interactions and solub ...

Nature Publishing Group2014

New Tools for Hydrogel-Based 3D Bioprinting

Andrea Negro

The in vitro recapitulation of tissue and organ function represents one of the main objectives of tissue engineering. Developments in this field have numerous applications, from alleviating the shortage of donor organs to providingmore representative pla ...

EPFL2014

Artificial niche microarrays for probing single stem cell fate in high throughput

Matthias Lütolf, Stefan Kobel, Samy Gobaa, Andrea Negro

To understand the regulatory role of niches in maintaining stem-cell fate, multifactorial in vitro models are required. These systems should enable analysis of biochemical and biophysical niche effectors in a combinatorial fashion and in the context of a p ...

Nature Publishing Group2011