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Francisco Javier Perez Saez

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Publications associées (21)

Rainfall as a driver of epidemic cholera: Comparative model assessments of the effect of intra-seasonal precipitation events

Andrea Rinaldo, Damiano Pasetto, Francisco Javier Perez Saez, Joseph Chadi Benoit Lemaitre, Carla Sciarra

The correlation between cholera epidemics and climatic drivers, in particular seasonal tropical rainfall, has been studied in a variety of contexts owing to its documented relevance. Several mechanistic models of cholera transmission have included rainfall ...

2019

Gene drives for schistosomiasis transmission control

Francisco Javier Perez Saez

Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas. Although mass drug administr ...

2019

Modelled effects of prawn aquaculture on poverty alleviation and schistosomiasis control

Andrea Rinaldo, Lorenzo Mari, Francisco Javier Perez Saez, Marino Gatto

Recent evidence suggests that snail predators may aid efforts to control the human parasitic disease schistosomiasis by eating aquatic snail species that serve as intermediate hosts of the parasite. Here, potential synergies between schistosomiasis control ...

NATURE PUBLISHING GROUP2019

A field-based modelling framework of the ecohydrology of schistosomiasis

Francisco Javier Perez Saez

Successful control of schistosomiasis, a water-borne parasitic disease, is challenged by the intricacy of the wormâ s lifecycle, which depends on aquatic snail intermediate hosts, and involves environmental, ecologic, and socio-economic factors. Current s ...

EPFL2018

Heterogeneity in schistosomiasis transmission dynamics

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Francisco Javier Perez Saez, Marino Gatto

Simple models of disease propagation often disregard the effects of transmission heterogeneity on the ecological and epidemiological dynamics associated with host-parasite interactions. However, for some diseases like schistosomiasis, a widespread parasiti ...

Academic Press Ltd- Elsevier Science Ltd2017

Incorporating the ecology of intermediate hosts of schistosomiasis into spatially explicit models of disease transmission in seasonal climates

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez, Marino Gatto

Wiley2017

Classification and prediction of river network ephemerality and its relevance for waterborne disease epidemiology

Andrea Rinaldo, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez

The transmission of waterborne diseases hinges on the interactions between hydrology and ecology of hosts, vectors and parasites, with the long-term absence of water constituting a strict lower bound. However, the link between spatio-temporal patterns of h ...

Elsevier Sci Ltd2017

Hydrology and density feedbacks control the ecology of intermediate hosts of schistosomiasis across habitats in seasonal climates

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez, Marino Gatto

We report about field and theoretical studies on the ecology of the aquatic snails (Bulinus spp. and Biomphalaria pfeifferi) that serve as obligate intermediate hosts in the complex life cycle of the parasites causing human schistosomiasis. Snail abundance ...

Natl Acad Sciences2016

Climate-driven endemic cholera is modulated by human mobility in a megacity

Andrea Rinaldo, Francisco Javier Perez Saez

Although a differential sensitivity of cholera dynamics to climate variability has been reported in the spatially heterogeneous megacity of Dhaka, Bangladesh, the specific patterns of spread of the resulting risk within the city remain unclear. We build on ...

Elsevier2016

Spatial patterns of schistosomiasis in Burkina Faso: relevance of human mobility and water resources development

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez, Marino Gatto

Wiley-Blackwell2015

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Rainfall as a driver of epidemic cholera: Comparative model assessments of the effect of intra-seasonal precipitation events

Andrea Rinaldo, Damiano Pasetto, Francisco Javier Perez Saez, Joseph Chadi Benoit Lemaitre, Carla Sciarra

2019

Incorporating the ecology of intermediate hosts of schistosomiasis into spatially explicit models of disease transmission in seasonal climates

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez, Marino Gatto

Wiley2017

Hydrology and density feedbacks control the ecology of intermediate hosts of schistosomiasis across habitats in seasonal climates

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez, Marino Gatto

Natl Acad Sciences2016

Spatial patterns of schistosomiasis in Burkina Faso: relevance of human mobility and water resources development

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Theophile Mande, Francisco Javier Perez Saez, Marino Gatto

Wiley-Blackwell2015