Publications de Loïc Nicolas Jeanbourquin

Contributions to the Chemistry of N2O and 1-Alkynyltriazenes

This thesis describes the utilization of nitrous oxide N2O as an oxidant in oxidative cou-pling reactions and as a nitrogen atom donor in the synthesis of 1-alkynyltriazene and further reactivity of the latter. An overview of N2O and its reactivity is give ...

EPFL2018

Gold-Catalyzed Synthesis of 1,3-Diaminopyrazoles from 1-Alkynyltriazenes and Imines

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Loïc Nicolas Jeanbourquin

A new procedure for the synthesis of highly substituted 1,3-diaminopyrazoles is described. As substrates, we have employed 1-alkynyltriazenes and imines. The formation of pyrazoles was achieved by two-fold C–N coupling reactions in the presence of (JohnPho ...

2017

Synthesis and Reactivity of 1-Allenyltriazenes

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Loïc Nicolas Jeanbourquin

1-Aryl-3,3-dialkyltriazenes have received considerable attention in the context of synthetic and medicinal chemistry. In contrast, the chemistry of other unsaturated triazenes is largely unexplored. The synthesis of 1-allenyltriazenes is described. This ne ...

2017

1-Alkynyltriazenes as Functional Analogues of Ynamides

Rosario Scopelliti, Kay Severin, Jérôme Waser, Gregor Kiefer, Sophie Lucie Racine, Loïc Nicolas Jeanbourquin, Florian Gérald Abela, Daniele Perrotta

The chemical reactivity of 1-alkynyltriazenes has been investigated and is found to parallel the reactivity of ynamides. The similarity in reactivity of these two classes of compounds is demonstrated by addition reactions with acids, by cycloaddition react ...

Wiley-Blackwell2015

Oxidative Coupling Reactions of Grignard Reagents with Nitrous Oxide

Kay Severin, Gregor Kiefer, Loïc Nicolas Jeanbourquin

Catalysis with laughing gas: N2O in combination with transition-metal catalysts allow the oxidative homo- and cross-coupling of Grignard reagents. The reactions can be performed under mild conditions despite the inert character of N2O. ...

Wiley-Blackwell2013