Suliana Manley

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Publications associées (87)

Fluorescent D-Amino Acids for Super-resolution Microscopy of the Bacterial Cell Wall

Suliana Manley, Luc Reymond, Ophélie Rutschmann, Willi Leopold Stepp, Juliette Griffie, Chen Zhang, Jiangtao Qiao, Faustine Ambroisine Charline Ryckebusch

Fluorescent D-amino acids (FDAAs) have previ-ously been developed to enable in situ highlighting of locations of bacterial cell wall growth. Most bacterial cells lie at the edge of the diffraction limit of visible light; thus, resolving the precise details ...

2022

Optical microscopy gets down to angstroms

Suliana Manley, Giorgio Tortarolo

Super-resolution microscopy at angstrom precision could pave the way to optical structural biology in cells. ...

NATURE PORTFOLIO2022

Flipper Probes for the Community

Suliana Manley, Dora Mahecic

This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR (R), ER Flippe ...

SWISS CHEMICAL SOC2021

Single-molecule localization microscopy

Suliana Manley, Juliette Griffie

Single-molecule localization microscopy (SMLM) describes a family of powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scal ...

SPRINGERNATURE2021

Mitochondrial membrane tension governs fission

Suliana Manley, Lina Carlini, Dora Mahecic, Tatjana Isabelle Kleele

During mitochondrial fission, key molecular and cellular factors assemble on the outer mitochondrial membrane, where they coordinate to generate constriction. Constriction sites can eventually divide or reverse upon disassembly of the machinery. However, a ...

CELL PRESS2021

Experimental Combination of Super-Resolution Optical Fluctuation Imaging with Structured Illumination Microscopy for Large Fields-of-View

Aleksandra Radenovic, Suliana Manley, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Kristin Stefanie Grussmayer, Dora Mahecic

All fluorescence super-resolution microscopy techniques present trade-offs between, for example, resolution, acquisition speed, and live-cell compatibility. Structured illumination microscopy (SIM) improves the resolution through successive imaging of the ...

AMER CHEMICAL SOC2021

3D Structure From 2D Microscopy Images Using Deep Learning

Suliana Manley, Christian Sieben

Understanding the structure of a protein complex is crucial in determining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional. Recent advances i ...

Frontiers Media Sa2021

Voices Physics meets biology: The joining of two forces to further our understanding of cellular function

Suliana Manley

CELL PRESS2021

Distinct fission signatures predict mitochondrial degradation or biogenesis

Suliana Manley, Hélène Danielle Perreten Lambert, Julius Hans Bernd Winter, Dora Mahecic, Timo Henry René Rey, Tatjana Isabelle Kleele

Mitochondrial fission is a highly regulated process that, when disrupted, can alter metabolism, proliferation and apoptosis(1-3). Dysregulation has been linked to neurodegeneration(3,4), cardiovascular disease(3) and cancer(5). Key components of the fissio ...

2021

Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations

Suliana Manley, Christian Sieben

Inferring the organization of fluorescently labeled nanosized structures from single molecule localization microscopy (SMLM) data, typically obscured by stochastic noise and background, remains challenging. To overcome this, we developed a method to extrac ...

AMER CHEMICAL SOC2021

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Flipper Probes for the Community

Suliana Manley, Dora Mahecic

SWISS CHEMICAL SOC2021

Mitochondrial membrane tension governs fission

Suliana Manley, Lina Carlini, Dora Mahecic, Tatjana Isabelle Kleele

CELL PRESS2021

Experimental Combination of Super-Resolution Optical Fluctuation Imaging with Structured Illumination Microscopy for Large Fields-of-View

Aleksandra Radenovic, Suliana Manley, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Kristin Stefanie Grussmayer, Dora Mahecic

AMER CHEMICAL SOC2021

NATURE PORTFOLIO2022