Publications de Wenqi You Dubout

An Algorithmic Approach to Personalized Drug Concentration Predictions

EPFL2014

Safe Implementation of Embedded Software for a Portable Device Supporting Drug Administration

Giovanni De Micheli, Yann Thoma, Alena Simalatsar, Wenqi You Dubout

Poor adherence to medical regimen causes approximately 33% to 69% of medication-related hospitalizations and accounts for $100 billion in annual health care costs. In this paper we address the problem of unintentional non adherence, when patient fails to t ...

IEEE2014

Representation of Medical Guidelines with a Computer Interpretable Model

Giovanni De Micheli, Alena Simalatsar, Wenqi You Dubout

Nowadays medical software is tightly coupled with medical devices that perform patient state monitoring and lately even some basic treatment procedures. Medical guidelines (GLs) can be seen as specification of a medical system which requires their computer ...

World Scientific Publ Co Pte Ltd2014

Personalized Drug Administrations Using Support Vector Machine

Giovanni De Micheli, Alena Simalatsar, Wenqi You Dubout

The decision-making process regarding drug dose, regularly used in everyday medical practice, is critical to patients’ health and recovery. It is a challenging process, especially for a drug with narrow therapeutic ranges, in which a medical doctor decides ...

2013

Parameterized SVM for Personalized Drug Concentration Prediction

Giovanni De Micheli, Alena Simalatsar, Wenqi You Dubout

This paper proposes a parameterized Support Vector Machine (ParaSVM) approach for modeling the Drug Concentration to Time (DCT) curves. It combines the merits of Support Vector Machine (SVM) algorithm that considers various patient features and an analytic ...

2013

A Drug Administration Decision Support System

Giovanni De Micheli, Alena Simalatsar, Wenqi You Dubout

Drug delivery is one of the most common clinical routines in hospitals, and is critical to patients’ health and recovery. It includes a decision making process in which a medical doctor decides the amount (dose) and frequency (dose interval) on the basis o ...

2012

RANSAC-based Enhancement in Drug Concentration Prediction Using Support Vector Machine

Giovanni De Micheli, Alena Simalatsar, Wenqi You Dubout

Training Support Vector Machines (SVMs) to predict drugs concentrations is often difficult because of the high level of noise in the training data, due to various kinds of measurement errors. We apply RANdom SAmple Consensus (RANSAC) algorithm in this pape ...

2012

Example-based Support Vector Machine for Drug Concentration Analysis

Giovanni De Micheli, Wenqi You Dubout

Machine learning has been largely applied to ana- lyze data in various domains, but it is still new to personalized medicine, especially dose individualization. In this paper, we focus on the prediction of drug concentrations using Support Vector Machines ...

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