Publications de Sanja Blaskovic

Mechanism and Function of S-palmitoylation in Capillary Morphogenesis Gene 2

EPFL2014

Mechanistic effects of protein palmitoylation and the cellular consequences thereof

Françoise Gisou van der Goot Grunberg, Sanja Blaskovic, Mathieu Blanc

S-palmitoylation involves the attachment of a 16-carbon long fatty acid chain to the cysteine residues of proteins. The process is enzymatic and dynamic with DHHC enzymes mediating palmitoylation and acyl-protein thioesterases reverting the reaction. Prote ...

Elsevier Ireland Ltd2014

Palmitoylation, pathogens and their host

Françoise Gisou van der Goot Grunberg, Sanja Blaskovic, Mathieu Blanc

S-Palmitoylation, the only reversible post-translational lipid modification, confers unique biochemical and functional properties to proteins. Although it has long been known that viral proteins are palmitoylated, recent studies reveal that this modificati ...

2013

Palmitoylated calnexin is a key component of the ribosome-translocon complex

Françoise Gisou van der Goot Grunberg, Matteo Dal Peraro, Thomas Lemmin, Laurence Gouzi Abrami, Béatrice Kunz, Sanja Blaskovic

A third of the human genome encodes N-glycosylated proteins. These are co-translationally translocated into the lumen/membrane of the endoplasmic reticulum (ER) where they fold and assemble before they are transported to their final destination. Here, we s ...

2012