Personne

Nicolas Vachicouras

Cette personne n’est plus à l’EPFL

Publications associées (16)

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Stéphanie Lacour, Florent-Valéry Coen, Nicolas Vachicouras

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...
SPRINGER2022

Method for labelling a device and devices obtanaible therefrom

Nicolas Vachicouras, Florian Dylan Fallegger, Ludovic Serex

Disclosed herein is a method for labelling a portion of a device, said method comprising the steps of providing a first substrate layer of a transparent or translucent material, depositing a first coloured material onto said first substrate layer in a labe ...
2022

Viscoelastic surface electrode arrays to interface with viscoelastic tissues

Stéphanie Lacour, Alix Esther Anne Trouillet, Nicolas Vachicouras, Florian Dylan Fallegger, Christina Myra Tringides

Bioelectronic interfacing with living tissues should match the biomechanical properties of biological materials to reduce damage to the tissues. Here, the authors present a fully viscoelastic microelectrode array composed of an alginate matrix and carbon-b ...
NATURE RESEARCH2021

Dimensional scaling of thin-film stimulation electrode systems in translational research

Stéphanie Lacour, Nicolas Vachicouras, Giuseppe Schiavone

Objective. Electrical stimulation of biological tissue is an established technique in research and clinical practice that uses implanted electrodes to deliver electrical pulses for a variety of therapies. Significant research currently explores new electro ...
2021

Soft, Implantable Bioelectronic Interfaces for Translational Research

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Sébastien Jiguet, Ivan Furfaro, Evgenia Vladimirova Roussinova, Marco Capogrosso, Nicolas Vachicouras, Giuseppe Schiavone, Florian Dylan Fallegger, Beatrice Barra, Xiaoyang Kang, Andreas Rowald, Simon Borgognon, Ismael Seanez Gonzalez

The convergence of materials science, electronics, and biology, namely bioelectronic interfaces, leads novel and precise communication with biological tissue, particularly with the nervous system. However, the translation of lab‐based innovation toward cli ...
2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Nicolas Vachicouras

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...
LIPPINCOTT WILLIAMS & WILKINS2020

Biomedical device comprising a mechanically adaptive member

Stéphanie Lacour, Nicolas Vachicouras, Jennifer Mary Adrienne Alice Macron

A biomedical device having improved handling features to be easily inserted into a cavity or recess is disclosed, as well as methods for using thereof, said device comprising a flat and soft substrate, comprising electrically conductive tracks, configured ...
2020

Soft microfabricated neural implants: a path towards translational implementation

Nicolas Vachicouras

Neuroprosthetics are a class of medical devices that aim to restore lost or impaired functions of the nervous system by electrical stimulation or recording of neural tissue. State of the art neural implants suffer today from a mechanical mismatch compared ...
EPFL2019

Auditory Brainstem Implants: Recent Progress and Future Perspectives

Stéphanie Lacour, Nicolas Vachicouras

The auditory brainstem implant (ABI) was first developed nearly 40 years ago and provides auditory rehabilitation to patients who are deaf and ineligible for cochlear implant surgery due to abnormalities of the cochlea and cochlear nerve. The aims of the f ...
2019

Microstructured thin-film electrode technology enables proof of concept of scalable, soft auditory brainstem implants

Stéphanie Lacour, Nicolas Vachicouras, Florian Dylan Fallegger, Christina Myra Tringides, Jennifer Mary Adrienne Alice Macron, Valentina Marie Paggi, Yohann Daniel André Thenaisie

Auditory brainstem implants (ABIs) provide sound awareness to deaf individuals who are not candidates for the cochlear implant. The ABI electrode array rests on the surface of the cochlear nucleus (CN) in the brainstem and delivers multichannel electrical ...
2019

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