Publications de Aleksandra Zabuga

Infrared Spectroscopy as a Probe of Electronic Energy Transfer

Thomas Rizzo, Valeriu Scutelnic, Antonio Prlj, Aleksandra Zabuga

We have combined electronic and vibrational spec- troscopy in a cryogenic ion trap to produce highly resolved, conformer-selective spectra for the ground and excited states of a peptide containing two chromophores. These spectra permit us to determine the ...

2018

IR-induced conformational isomerization of a helical peptide in a cold ion trap

Thomas Rizzo, Aleksandra Zabuga, Caroline Seaiby, Annette Svendsen

In this work we use laser-induced population transfer techniques to study the conformational isomerization of a helical peptide, Ac-Phe-(Ala)5-LysH+, in a cold ion trap. In one scheme, called IR-UV hole-filling spectroscopy, a single conformation is select ...

American Institute of Physics2016

Franck–Condon-like Progressions in Infrared Spectra of Biological Molecules

Thomas Rizzo, Michael Zachary Kamrath, Aleksandra Zabuga

Infrared spectra in the NH stretch region are often used for structure determination of gas-phase biological molecules. Vibrational couplings complicate the structure determination process by giving rise to additional vibrational bands along with the expec ...

American Chemical Society2015

Fragmentation mechanism of UV-excited peptides in the gas phase

Thomas Rizzo, Oleg Boyarkine, Michael Zachary Kamrath, Aleksandra Zabuga

We present evidence that following near-UV excitation, protonated tyrosine- or phenylalanine–containing peptides undergo intersystem crossing to produce a triplet species. This pathway competes with direct dissociation from the excited electronic state and ...

American Institute of Physics2014

Dynamics of UV-excited, protonated peptides in the gas phase

Aleksandra Zabuga

The scope of this thesis is the electronically excited state dynamics of protonated peptides and their photofragmentation mechanism. UV radiation induces fragmentation of biological molecules and might cause various diseases, such as cataracts or skin canc ...

EPFL2014