Martin Ehrbar

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (27)

3D growth factor patterned cell substrates to locally control cellular behavior

Matthias Lütolf, Philipp Sebastian Lienemann, Yannick Robert Devaud, Martin Ehrbar, Vincent Milleret

Wiley-Blackwell2014

In situ cell manipulation through enzymatic hydrogel photopatterning

Matthias Lütolf, Jeffrey Alan Hubbell, Mikaël Martino, Laura Kolb, Katarzyna Mosiewicz, Martin Ehrbar

The physicochemical properties of hydrogels can be manipulated in both space and time through the controlled application of a light beam. However, methods for hydrogel photopatterning either fail to maintain the bioactivity of fragile proteins and are thus ...

Nature Publishing Group2013

A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells

Stéphanie Elisabeth Metzger, Martin Ehrbar

Growth and differentiation of multicellular systems is orchestrated by spatially restricted gene expression programs in specialized subpopulations. The targeted manipulation of such processes by synthetic tools with high-spatiotemporal resolution could, th ...

Oxford University Press2013

Proteolytic Processing Regulates Placental Growth Factor Activities

Jeffrey Alan Hubbell, Stéphanie Elisabeth Metzger, Martin Ehrbar, Manuel Koch

Placental growth factor (PlGF) is a critical mediator of blood vessel formation, yet mechanisms of its action and regulation are incompletely understood. Here we demonstrate that proteolytic processing regulates the biological activity of PlGF. Specificall ...

Amer Soc Biochemistry Molecular Biology Inc2013

Pharmacologically Controlled Protein Switch for ON-OFF Regulation of Growth Factor Activity

Philipp Sebastian Lienemann, Martin Ehrbar

The precise manipulation of growth factor signaling is central to the progress of tissue engineering. Methods for direct time-resolved activation of signaling pathways through controlled receptor dimerization have been reported; however, these suffer from ...

Nature Publishing Group2013

A Versatile Approach to Engineering Biomolecule-Presenting Cellular Microenvironments

Matthias Lütolf, Philipp Sebastian Lienemann, Martin Ehrbar

Wiley-Blackwell2013

Engineering biomimetic hydrogels for induced recruitment of mesenchymal stem cells in vitro and in vivo

Matthias Lütolf, Olaia Maria Naveiras Torres-Quiroga, Philipp Sebastian Lienemann, Martin Ehrbar

Wiley-Blackwell2012

Keynote: Engineering homing and differentiation of mesenchymal progenitor cells during bone healing

Matthias Lütolf, Philipp Sebastian Lienemann, Martin Ehrbar

Wiley-Blackwell2012

Longterm cell-demanded release of TG-VEGF for the development of mature vascular networks in vivo

Jeffrey Alan Hubbell, Kristen Lorentz, Martin Ehrbar, Daniel Eberli

Wiley-Blackwell2012

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

Matthias Lütolf, Adrian Ranga, Martin Ehrbar

Engineered artificial microenvironments hold enormous potential as models to study developmental, physiological, pathological, and regenerative processes under highly defined conditions. Such platforms aim at bridging the gap between traditional in vitro 2 ...

2011

Page 2 sur 3

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

Matthias Lütolf, Adrian Ranga, Martin Ehrbar

2011