Publications de Jérôme Blanc

Lamellar Schwann Cells in the Pacinian Corpuscle Potentiate Vibration Perception

Graham Knott, Jérôme Blanc, Mary-Claude Croisier-Coeytaux

Pacinian corpuscles are among the most sensitive mechanoreceptors found in vertebrates, and they are tuned to vibrations in the highest perceptible frequency range (100 to 2000 Hz). One of their anatomical hallmarks is the onion-like cell layers surroundin ...

AMER ASSOC ADVANCEMENT SCIENCE2025

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

Graham Knott, Jérôme Blanc, Christina Georgiou, Kok Sin Lee

Structural synaptic plasticity may underlie experience and learning-dependent changes in cortical circuits. In contrast to excitatory pyramidal neurons, insight into the structural plasticity of inhibitory neurons remains limited. Interneurons are divided ...

NATURE PORTFOLIO2022

3D Ultrastructure of Synaptic Inputs to Distinct GABAergic Neurons in the Mouse Primary Visual Cortex

Carl Petersen, Graham Knott, Jérôme Blanc, Catherine Maclachlan

Synapses are the fundamental elements of the brain's complicated neural networks. Although the ultrastructure of synapses has been extensively studied, the difference in how synaptic inputs are organized onto distinct neuronal types is not yet fully unders ...

OXFORD UNIV PRESS INC2021

Ultrastructural comparison of dendritic spine morphology preserved with cryo and chemical fixation

Carl Petersen, Graham Knott, Jérôme Blanc, Natalya Korogod

Previously, we showed that cryo fixation of adult mouse brain tissue gave a truer representation of brain ultrastructure in comparison with a standard chemical fixation method (Korogod et al., 2015). Extracellular space matched physiological measurements, ...

2020

NeuroMorph: A Software Toolset for 3D Analysis of Neurite Morphology and Connectivity

Graham Knott, Jérôme Blanc, Anne Alison Jorstad

The geometries of axons, dendrites and their synaptic connections provide important information about their functional properties. These can be collected directly from measurements made on serial electron microscopy images. However, manual and automated se ...

2018