Publications de Ying-Chia Lin | EPFL Graph Search

Tractography passes the test: Results from the diffusion-simulated connectivity (disco) challenge

Jean-Philippe Thiran, Gabriel Girard, Erick Jorge Canales Rodriguez, Juan Luis Villarreal Haro, Alessandro Daducci, Alonso Ramirez Manzanares, Marco Pizzolato, Ying-Chia Lin, Sara Sedlar, Caio Seguin

Estimating structural connectivity from diffusion-weighted magnetic resonance imaging is a challenging task, partly due to the presence of false-positive connections and the misestimation of connection weights. Building on previous efforts, the MICCAI-CDMR ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2023

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing‐remitting multiple sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Jonas Richiardi, Gunnar Krüger, Alexis Roche, Guillaume Bonnier

Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

Wiley-Blackwell2015

Multicontrast MRI Quantification of Focal Inflammation and Degeneration in Multiple Sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Introduction. Local microstructural pathology in multiple sclerosis patients might influence their clinical performance. This study applied multicontrast MRI to quantify inflammation and neurodegeneration in MS lesions. We explored the impact of MRI-based ...

Hindawi Publishing Corporation2015

Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Conventional magnetic resonance imaging (MRI) of patients with multiple sclerosis provides only limited insights into the nature of brain tissue damage with modest clinical-radiological correlations. In this study, quantitative and semi-quantitative MRI te ...

2014

Cerebellar Connectomics Provide New Biomarkers in Early Multiple Sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano, Alessandro Daducci, Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alexis Roche, Jonas Richiardi, Guillaume Bonnier

The cerebellum is involved in multiple sclerosis (MS), but its implication in early phases is still poorly understood. We investigated structural and functional cerebellar connectivity alterations in early and minimally impaired MS patients, and their corr ...

2014

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014

Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

2014

Quantitative comparison of reconstruction methods for intra-voxel fiber recovery from diffusion MRI

Jean-Philippe Thiran, Yves Wiaux, Alessandro Daducci, Erick Jorge Canales Rodriguez, Ying-Chia Lin, Alonso Ramirez Manzanares, Maxime Descoteaux, Gloria Menegaz, Mathews Jacob

Validation is arguably the bottleneck in the diffusion MRI community. This paper evaluates and compares 20 algorithms for recovering the local intra-voxel fiber structure from diffusion MRI data and is based on the results of the "HARDI reconstruction chal ...

Institute of Electrical and Electronics Engineers2014