Personne

Benjamin Rauwel

Cette personne n’est plus à l’EPFL

Publications associées (5)

KAP1 facilitates reinstatement of heterochromatin after DNA replication

Didier Trono, Priscilla Turelli, Julien Léonard Duc, Sandra Eloise Kjeldsen, Annamaria Kauzlaric, Andrea Coluccio, Julien Paul André Pontis, Suk Min Jang, Benjamin Rauwel, Geneviève Almouzni

During cell division, maintenance of chromatin features from the parental genome requires their proper establishment on its newly synthetized copy. The loss of epigenetic marks within heterochromatin, typically enriched in repetitive elements, endangers ge ...

2018

Methods for purging isolated organs and cells from latent human cytomegalovirus

Didier Trono, Benjamin Rauwel

The present invention relates to a method for purging ex vivo isolated organs or isolated cells from latent human cytomegalovirus (HCMV). The invention further relates to a compound for use in a method for treating HCMV infection. ...

2015

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

Didier Trono, Isabelle Barde, Adamantia Kapopoulou, Marco Cassano, Suk Min Jang, Benjamin Rauwel

Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are normally controlled by the immune system, but can be fat ...

2015

Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Didier Trono, Priscilla Turelli, Evaristo Jose Planet Letschert, Bastien Mangeat, Marc Samuel Friedli, Adamantia Kapopoulou, Gabriela Ecco, Helen Mary Rowe, Benjamin Rauwel, Carmen Maria Unzu Ezquerro

Endogenous retroelements (EREs) account for about half of the mouse or human genome, and their potential as insertional mutagens and transcriptional perturbators is suppressed by early embryonic epigenetic silencing. Here, we asked how ERE control is maint ...

Cold Spring Harbor Lab Press, Publications Dept2014

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During hematopoiesis, lineage- and stage-specific transcription factors work in concert with chromatin modifiers to direct the differentiation of all blood cells. Here, we explored the role of KRAB-containing zinc finger proteins (KRAB-ZFPs) and their cofa ...

Amer Assoc Advancement Science2013

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