Publications de Marco Piccinini

Peri-implant bone adaptations to overloading in rat tibiae: experimental investigations and numerical predictions

John Botsis, Joël Cugnoni, Marco Piccinini

Objectives(i) To assess the effects of mechanical overloading on implant integration in rat tibiae, and (ii) to numerically predict peri-implant bone adaptation. Materials and methodsTranscutaneous titanium implants were simultaneously placed into both tib ...

Wiley-Blackwell2016

Numerical prediction of peri-implant bone adaptation: Comparison of mechanical stimuli and sensitivity to modeling parameters

John Botsis, Joël Cugnoni, Marco Piccinini

Long term durability of osseointegrated implants depends on bone adaptation to stress and strain occurring in proximity of the prosthesis. Mechanical overloading, as well as disuse, may reduce the stability of implants by provoking bone resorption. However ...

Elsevier2016

Factors affecting subject-specific finite element models of implant-fitted rat bone specimens: critical analysis of a technical protocol

John Botsis, Joël Cugnoni, Marco Piccinini

The authors propose a protocol to derive finite element (FE) models from micro computer tomography scans of implanted rat bone. A semi-automatic procedure allows segmenting the images using specimen-specific bone mineral density (BMD) thresholds. An open-s ...

Taylor & Francis2014

Influence of gait loads on implant integration in rat tibiae: Experimental and numerical analysis

John Botsis, Joël Cugnoni, Marco Piccinini

Implanted rat bones play a key role in studies involving fracture healing, bone diseases or drugs delivery among other themes. In most of these studies the implants integration also depends on the animal daily activity and musculoskeletal loads, which affe ...

Elsevier2014

Prediction of peri-implant bone adaptation to mechanical environments : theoretical developments and experimental validation

Marco Piccinini

EPFL2014