Publications de Céline Fournier

Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice

Maria del Carmen Sandi Perez, Jocelin Grosse, Alexandre Claude Gustave Bacq, Céline Fournier

Early-life stress is a key risk factor for the development of neuropsychiatric disorders later in life. Neuronal cell adhesion molecules have been strongly implicated in the pathophysiology of psychiatric disorders and in modulating social behaviors associ ...

2015

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Michael van der Kooij, Martina Fantin, Céline Fournier

Chronic stress is a risk factor for the development of psychopathologies characterized by cognitive dysfunction and deregulated social behaviours. Emerging evidence suggests a role for cell adhesion molecules, including nectin-3, in the mechanisms that un ...

Nature Research2014

Hippocampal neuroligin-2 overexpression leads to reduced aggression and inhibited novelty reactivity in rats

Maria del Carmen Sandi Perez, Jocelin Grosse, Orbicia Riccio Wicht, Olivia Zanoletti, Céline Fournier

Disturbances of the excitation/inhibition (E/I) balance in the brain were recently suggested as potential factors underlying disorders like autism and schizophrenia resulting in associated behavioral alterations including changes in social and emotional be ...

Public Library of Science2013

The interplay of conditional NCAM-knockout and chronic unpredictable stress leads to increased aggression in mice

Maria del Carmen Sandi Perez, Jocelin Grosse, Orbicia Riccio Wicht, Olivia Zanoletti, Céline Fournier

The neural cell adhesion molecule (NCAM) is a key regulator of brain plasticity. Substantial evidence indicates that NCAM is down-regulated by exposure to sustained stress and chronic stress seems to lead to increased aggression. In addition, constitutiona ...

Informa Healthcare2013