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Lionel André Maurizi

Cette personne n’est plus à l’EPFL

Publications associées (19)

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Beyond Unpredictability: The Importance of Reproducibility in Understanding the Protein Corona of Nanoparticles

Heinrich Hofmann, Diego Chiappe, Lionel André Maurizi, Sandra Caroline Galmarini, Nadia Rachel Von Moos, Noëlie Cayla

While it is well established that the surface of a nanoparticle plays a pivotal role for the protein corona, the vast number of proteins present in biological media render general conclusions about affinities between nanoparticle surfaces and proteins nont ...

AMER CHEMICAL SOC2018

Superparamagnetic nanohybrids with cross-linked polymers providing higher in vitro stability

Heinrich Hofmann, Lionel André Maurizi

A simple, rapid, reproducible, and scalable method for generating highly stable cross-linked superparamagnetic nanohybrids was developed. Pre-coating of superparamagnetic iron oxide nanoparticle surfaces with a biocompatible polymer, hydroxy polyvinyl alco ...

Springer Verlag2017

Modification of the surface of superparamagnetic iron oxide nanoparticles to enable their safe application in humans

Heinrich Hofmann, Lionel André Maurizi

Combined individually tailored methods for diagnosis and therapy (theragnostics) could be beneficial in destructive diseases, such as rheumatoid arthritis. Nanoparticles are promising candidates for theragnostics due to their excellent biocompatibility. Na ...

Dove Medical Press Ltd2016

Effects of PVA-coated nanoparticles on human T helper cell activity

Heinrich Hofmann, Lionel André Maurizi

Superparamagnetic iron oxide nanoparticles (SPION) are used as high-sensitive enhancer for magnetic resonance imaging, where they represent a promising tool for early diagnosis of destructive diseases such as rheumatoid arthritis (RA). Since we could demon ...

Elsevier2016

Pro-oxidant effects of nano-TiO2 on Chlamydomonas reinhardtii during short-term exposure

Olivier Martin, Paul Bowen, Christian Santschi, Lionel André Maurizi, Volodymyr Koman, Nadia Rachel Von Moos, Amarnath Jayaprakash

This study sheds light on the short-term dynamics of pro-oxidant processes related to the exposure of C. reinhardtii microalgae to nano-TiO2 using (a) conventional fluorescence probes for cellular pro-oxidant process and (b) a recently developed cytochrome ...

Royal Soc Chemistry2016

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As nanoparticles (NPs) are increasingly used in many applications their safety and efficient applications in nanomedicine have become concerns. Protein coronas on nanomaterials' surfaces can influence how the cell "recognizes" nanoparticles, as well as the ...

Royal Soc Chemistry2015

This paper presents an original method to obtain, in one step, core/shell nanoparticles grafted covalently with polymer and functionalized with amino groups. By combining polyvinyl alcohol (PVA) and silica precursors, we were able to obtain silica-coated a ...

Hindawi Publishing Corporation2015

Nanotechnology is a rapidly expanding and highly promising new technology with many different fields of application. Consequently, the investigation of engineered nanoparticles in biological systems is steadily increasing. Questions about the safety of suc ...

Elsevier2015

BACKGROUND: Nanoparticle exposure in utero might not be a major concern yet, but it could become more important with the increasing application of nanomaterials in consumer and medical products. Several epidemiologic and invitro studies have shown that nan ...

Nat Inst of Environ Health Sciences / The National Institute of Environmental Health Sciences (NIEHS)2015

Nanotechnology provides new opportunities in human medicine, mainly for diagnostic and therapeutic purposes. The autoimmune disease rheumatoid arthritis (RA) is often diagnosed after irreversible joint structural damage has occurred. There is an urgent nee ...

Dove Medical Press Ltd2015