Personne
Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf
Cette personne n’est plus à l’EPFL
Publications associées (4)
Reactivation of Recall-Induced Neurons in the Infralimbic Cortex and the Basolateral Amygdala After Remote Fear Memory Attenuation
Johannes Gräff, Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf
Whether the attenuation of traumatic memories is mediated through the suppression of the original memory trace of fear by a new memory trace of safety, or through an updating of the original fear trace towards safety has been a long-standing question at th ...
FRONTIERS MEDIA SA2019In the pursuit of the fear engram: identification of neuronal circuits underlying the treatment of anxiety disorder
Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf
Fear and other anxiety disorders are extraordinarily robust and difficult to treat. Among the most effective treatments for anxiety disorders are exposure-based therapies, during which a patient is repeatedly confronted with the originally fear-eliciting s ...
EPFL2017Structural, Synaptic, and Epigenetic Dynamics of Enduring Memories
Johannes Gräff, Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf
Our memories are the records of the experiences we gain in our everyday life. Over time, they slowly transform from an initially unstable state into a long-lasting form. Many studies have been investigating from different aspects how a memory could persist ...
Hindawi Publishing Corp2016The H50Q Mutation Enhances alpha-Synuclein Aggregation, Secretion, and Toxicity
Giovanni Dietler, Hilal Lashuel, Anne-Laure Mahul Mellier, Bruno Claude Daniel Fauvet, Francesco Simone Ruggeri, Abid Oueslati, Martial Mbefo Kamdem, Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf, Filip Vercruysse
Over the last two decades, the identification of missense mutations in the alpha-synuclein (alpha-Syn) gene SNCA in families with inherited Parkinson disease (PD) has reinforced the central role of alpha-Syn in PD pathogenesis. Recently, a new missense mut ...
American Society for Biochemistry and Molecular Biology2014