Publications de Vasco Ledebur de Antas de Campos

A Label-Free, High-Throughput Phenotypic Screen Of Adipocytic Differentiation Modulators To Accelerate Hematopoietic Recovery

Bart Deplancke, Gerardo Turcatti, Vincent Roland Julien Gardeux, Fabien Kuttler, Damiano Banfi, Aurélien Laurent Jean-Charles Oggier, Vasco Ledebur de Antas de Campos, Pernille Yde Rainer

ELSEVIER SCIENCE INC2022

Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes

Olaia Maria Naveiras Torres-Quiroga, Charles Christopher Bataclan, Vasco Ledebur de Antas de Campos, Josefine Catharina Pedersen Tratwal, Daniel Naveed Tavakol

Bone marrow adipocytes (BMAds) constitute the most abundant stromal component of adult human bone marrow. Two subtypes of BMAds have been described, the more labile regulated adipocytes (rBMAds) and the more stable constitutive adipocytes (cBMAds), which d ...

FRONTIERS MEDIA SA2022

MarrowQuantAcross Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections

Olaia Maria Naveiras Torres-Quiroga, Olivier Burri, Rita Sarkis, Nicolas Kunz, Vasco Ledebur de Antas de Campos, Josefine Catharina Pedersen Tratwal, Frédérica Schyrr, Chiheb Boussema, Shanti Rojas-Sutterlin, Daniel Naveed Tavakol

The bone marrow (BM) exists heterogeneously as hematopoietic/red or adipocytic/yellow marrow depending on skeletal location, age, and physiological condition. Mouse models and patients undergoing radio/chemotherapy or suffering acute BM failure endure rapi ...

2020

MarrowQuant across Aging and Aplasia: A Digital Pathology Tool for Quantification of Bone Marrow Compartments in Histological Sections

Olaia Maria Naveiras Torres-Quiroga, Olivier Burri, Rita Sarkis, Nicolas Kunz, Vasco Ledebur de Antas de Campos, Josefine Catharina Pedersen Tratwal, Frédérica Schyrr, Shanti Rojas-Sutterlin

WILEY2020

Injectable, scalable 3D tissue-engineered model of marrow hematopoiesis

Olaia Maria Naveiras Torres-Quiroga, Vasco Ledebur de Antas de Campos, Amélie Barbara Hildegarde Béduer, Josefine Catharina Pedersen Tratwal, Patrick Burch, Daniel Naveed Tavakol, Martina Genta

2019

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

Johan Auwerx, Matthias Lütolf, Bart Deplancke, Carlos Canto Alvarez, Olaia Maria Naveiras Torres-Quiroga, George Coukos, Aurélien Laurent Jean-Charles Oggier, Dongryeol Ryu, Eija Riitta Pirinen, Loïc Tauzin

It has been recently shown that increased oxidative phosphorylation, as reflected by increased mitochondrial activity, together with impairment of the mitochondrial stress response, can severely compromise hematopoietic stem cell (HSC) regeneration. Here w ...

CELL PRESS2019

Metabolic and microenvironmental strategies to accelerate hematopoietic recovery post-aplasia

Vasco Ledebur de Antas de Campos

The procedure-associated mortality rate of bone marrow transplantations (BMT) remains close to 25%. The BMT is therefore only indicated for life-threatening diseases, with no replacement of this technology to be expected in the foreseeable future. Modest i ...

EPFL2019

Cellular Endogenous NAD(P)H Fluorescence as a Label-Free Method for the Identification of Erythrocytes and Reticulocytes

Mélanie Louise Tichet, Loïc Tauzin, Vasco Ledebur de Antas de Campos

2018

High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy

Gerardo Turcatti, Olaia Maria Naveiras Torres-Quiroga, Vasco Ledebur de Antas de Campos

American Society for Biochemistry and Molecular Biology Inc.2018

The NAD plus Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Matthias Lütolf, Bart Deplancke, Carlos Canto Alvarez, Olaia Maria Naveiras Torres-Quiroga, Dongryeol Ryu, George Coukos, Aurélien Laurent Jean-Charles Oggier, Eija Riitta Pirinen, Vasco Ledebur de Antas de Campos, Loïc Tauzin

AMER SOC HEMATOLOGY2018