Publications de David Allenson Borton

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease

Auke Ijspeert, Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Eduardo Martin Moraud, Jordan Squair, Giuseppe Schiavone, Léonie Asboth, Tomislav Milekovic

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor deficits that are resistant to currently available therapies. To alleviate these deficits, we developed a neuroprosthesis operating in closed loop that targets the dor ...

Nature Portfolio2023

Low-Dimensional Motor Cortex Dynamics Preserve Kinematics Information During Unconstrained Locomotion in Nonhuman Primates (vol

Grégoire Courtine, David Allenson Borton, Mehdi Aghagolzadeh

FRONTIERS MEDIA SA2020

A brain-spine interface alleviating gait deficits after spinal cord injury in primates

Silvestro Micera, Grégoire Courtine, Quentin Barraud, Jocelyne Bloch, Tomislav Milekovic, Eduardo Martin Moraud, Marco Capogrosso, Elodie Rey, Fabien Bertrand Paul Wagner, Jérôme Gandar

Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer interfaces(1-3) have directly linked cortical activity to electrical stimulation of muscles, and have th ...

Nature Publishing Group2016

Detection of Optogenetic Stimulation in Somatosensory Cortex by Non-Human Primates - Towards Artificial Tactile Sensation

Fabien Bertrand Paul Wagner, David Allenson Borton

Neuroprosthesis research aims to enable communication between the brain and external assistive devices while restoring lost functionality such as occurs from stroke, spinal cord injury or neurodegenerative diseases. In future closed-loop sensorimotor prost ...

Public Library of Science2014

Corticospinal neuroprostheses to restore locomotion after spinal cord injury

José del Rocio Millán Ruiz, Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Eduardo Martin Moraud, Pavel Musienko, Nikolaus Wenger, Ivan Rusev Minev, Marco Bonizzato, Janine Beauparlant

In this conceptual review, we highlight our strategy for, and progress in the development of corticospinal neuroprostheses for restoring locomotor functions and promoting neural repair after thoracic spinal cord injury in experimental animal models. We spe ...

Elsevier2014

Wireless Neurosensor for Full-Spectrum Electrophysiology Recordings during Free Behavior

Grégoire Courtine, Hao Li, David Allenson Borton, Yao Lu, Jean François Pierre Laurens

Brain recordings in large animal models and humans typically rely on a tethered connection, which has restricted the spectrum of accessible experimental and clinical applications. To overcome this limitation, we have engineered a compact, lightweight, high ...

Cell Press2014

Personalized neuroprosthetics

José del Rocio Millán Ruiz, Silvestro Micera, Grégoire Courtine, David Allenson Borton

Decades of technological developments have populated the field of neuroprosthetics with myriad replacement strategies, neuromodulation therapies, and rehabilitation procedures to improve the quality of life for individuals with neuromotor disorders. Despit ...

American Association for the Advancement of Science2013

A 100-Channel Hermetically Sealed Implantable Device for Chronic Wireless Neurosensing Applications

David Allenson Borton

A 100-channel fully implantable wireless broadband neural recording system was developed. It features 100 parallel broadband (0.1 Hz-7.8 kHz) neural recording channels, a medical grade 200 mAh Li-ion battery recharged inductively at 150 kHz, and data telem ...

Ieee-Inst Electrical Electronics Engineers Inc2013