Publications de Frédérica Schyrr

MarrowQuant 2.0: A Digital Pathology Workflow Assisting Bone Marrow Evaluation in Experimental and Clinical Hematology

Bart Deplancke, Olaia Maria Naveiras Torres-Quiroga, Giovanna Ambrosini, Olivier Burri, Arne Seitz, Rita Sarkis, Martin Weigert, Frédérica Schyrr, Mariangela Costanza

2023

The Bile Acid Receptor Tgr5 Regulates The Composition And Hematopoietic Support Capacity Of The Bone Marrow Microenvironment

Kristina Schoonjans, Alessia Perino, Antoine Jalil, Frédérica Schyrr, Alejandro Alonso Calleja

ELSEVIER SCIENCE INC2023

The bile acid receptor TGR5 regulates the hematopoietic support capacity of the bone marrow niche

Dominique Pioletti, Kristina Schoonjans, Alessia Perino, Ulrike Kettenberger, Antoine Jalil, Frédérica Schyrr, Alejandro Alonso Calleja

Smw Supporting Association2023

Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems

Johan Auwerx, Olaia Maria Naveiras Torres-Quiroga, Charles Christopher Bataclan, Frédérica Schyrr

Aging compromises hematopoietic and immune system functions, making older adults especially susceptible to hematopoietic failure, infections and tumor development, and thus representing an important medical target for a broad range of diseases. During agin ...

SPRINGERNATURE2023

New approaches to uncover the minimally functional hematopoietic niche using the adipocytic differentiation axis: pharmacological modulation and adrenal niche induction

Frédérica Schyrr

Hematopoietic Stem and Progenitor Cells (HSPCs) reside in their niche, a structure that regulates the balance of cellular quiescence, self-renewal and commitment towards differentiated cells. This highly plastic niche is formed by several cellular players, ...

EPFL2022

Differential Blood Counts Do Not Consistently Predict Clinical Measurements of Bone Mineral Density and Microarchitecture at Homeostasis

Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr

The hematopoietic stem cell niche constitutes a complex bone marrow (BM) microenvironment. Osteoporosis is characterized by both reduced bone mineral density (BMD) and microarchitectural deterioration, constituting the most frequent alteration of the BM mi ...

WILEY2022

MarrowQuantAcross Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections

Olaia Maria Naveiras Torres-Quiroga, Olivier Burri, Rita Sarkis, Nicolas Kunz, Vasco Ledebur de Antas de Campos, Josefine Catharina Pedersen Tratwal, Frédérica Schyrr, Chiheb Boussema, Shanti Rojas-Sutterlin, Daniel Naveed Tavakol

The bone marrow (BM) exists heterogeneously as hematopoietic/red or adipocytic/yellow marrow depending on skeletal location, age, and physiological condition. Mouse models and patients undergoing radio/chemotherapy or suffering acute BM failure endure rapi ...

2020

MarrowQuant across Aging and Aplasia: A Digital Pathology Tool for Quantification of Bone Marrow Compartments in Histological Sections

Olaia Maria Naveiras Torres-Quiroga, Olivier Burri, Rita Sarkis, Nicolas Kunz, Vasco Ledebur de Antas de Campos, Josefine Catharina Pedersen Tratwal, Frédérica Schyrr, Shanti Rojas-Sutterlin

WILEY2020

Blood cell production is not influenced by bone health status in homoeostasis - the CoLaus/OsteoLaus cohort

Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr

E M H SWISS MEDICAL PUBLISHERS LTD2019

Correlation study between osteoporosis and hematopoiesis in the context of adjuvant chemotherapy for breast cancer

Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr

Springer Verlag2018