Publications de Filiz Yesilköy

Imaging-based spectrometer-less optofluidic biosensors based on dielectric metasurfaces for detecting extracellular vesicles

Hatice Altug, Michele De Palma, Chiara Cianciaruso, Filiz Yesilköy, Yasaman Jahani, Eduardo Romero Arvelo

Biosensors are indispensable tools for public, global, and personalized healthcare as they provide tests that can be used from early disease detection and treatment monitoring to preventing pandemics. We introduce single-wavelength imaging biosensors capab ...

Nature Research2021

An integrated nanoplasmonic biosensor for monitoring cytokine secretion from single cells

Hatice Altug, Xiaokang Li, George Coukos, Filiz Yesilköy, Alexander Belushkin, Maria Soler Aznar

An innovative nanoplasmonic biosensor was presented for real-time label-free monitoring of cytokine secretion at single-cell resolution. This biosensor is integrated with a uniquely designed microfluidic device that provides a microchamber for cell incubat ...

IEEE2019

Ultrasensitive hyperspectral imaging and biodetection enabled by dielectric metasurfaces

Volkan Cevher, Hatice Altug, Filiz Yesilköy, Andreas Tittl, Yasaman Jahani, Eduardo Romero Arvelo, Mingkai Liu

Metasurfaces based on resonant subwavelength photonic structures enable novel ways of wavefront control and light focusing, underpinning a new generation of flat-optics devices. Recently emerged all-dielectric asymmetric metasurfaces, composed of arrays of ...

Nature Publishing Group2019

Label-free Bacteria Quantification in Blood Plasma by a Bioprinted Microarray Based Interferometric Point-of-Care Device

Hatice Altug, Filiz Yesilköy, Alexander Belushkin

Existing clinical methods for bacteria detection lack speed, sensitivity, and, importantly, point-of-care (PoC) applicability. Thus, finding ways to push the sensitivity of clinical PoC biosensing technologies is crucial. Here we report a portable PoC devi ...

AMER CHEMICAL SOC2019

Integrated Nanophotonic Biosensors for Point-of Care Diagnostics and Bioanalytical Applications

Hatice Altug, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Yasaman Jahani

In an effort to address the requirements of next-generation healthcare systems, including personalized medicine, point-of-care diagnostics, and global health surveillance, I will introduce imaging-based portable nanoplasmonic biosensors integrated with mic ...

IEEE2019

Plasmonic biosensor

Hatice Altug, Filiz Yesilköy, Alexander Belushkin

The present invention relates to a plasmonic biosensor system. The system includes a nano-hole array device comprising at least one nano-hole array (NHA) including at least one or a plurality of nano holes (NH), an image sensor (A3) for capturing light pro ...

2019

Rapid and Digital Detection of Inflammatory Biomarkers Enabled by a Novel Portable Nanoplasmonic Imager

Hatice Altug, Filiz Yesilköy, Alexander Belushkin

New point-of-care diagnostic devices are urgently needed for rapid and accurate diagnosis, particularly in the management of life-threatening infections and sepsis, where immediate treatment is key. Sepsis is a critical condition caused by systemic respons ...

2019

Self-assembly of nanostructured glass metasurfaces via templated fluid instabilities

Hatice Altug, Fabien Sorin, Wei Yan, Filiz Yesilköy, Alexis Gérald Page, Yunpeng Qu, Dang Tùng Nguyen, Arthur Le Bris, Louis Marie Philippe Martin-Monier, Kuan-Ting Ho

Modern devices require the tuning of the size, shape and spatial arrangement of nano-objects and their assemblies with nanometre-scale precision, over large-area and sometimes soft substrates. Such stringent requirements are beyond the reach of conventiona ...

Nature Publishing Group2019

All-dielectric Metasurfaces for Infrared Absorption Spectroscopy Applications

Hatice Altug, Filiz Yesilköy, Andreas Tittl, Aleksandrs Leitis, Mingkai Liu

We present a nanophotonic method capable of detecting mid-infrared molecular fingerprints without the need for spectrometry, frequency scanning, or moving mechanical parts. We leverage dielectric metasurfaces featuring ultra-sharp resonances each tuned to ...

IEEE2019

Label-free, scalable and point-of-care imaging platform for rapid analysis of biomarker

Hatice Altug, Filiz Yesilköy, Alexander Belushkin, Yasaman Jahani

We propose a disruptive point-of-care (PoC) imaging platform based on lens-free interference phase-contrast imaging for rapid detection of biomarker such as for sepsis and potentially other diseases (e.g. cancer). It enables simultaneous analysis of potent ...

SPIE-INT SOC OPTICAL ENGINEERING2019