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Atmospheric aerosols have significant effects on the climate and on human health. New particle formation (NPF) is globally an important source of aerosols but its relevance especially towards aerosol mass loadings in highly polluted regions is still contro ...
In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acq ...
2020
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Fluorescence molecular tomography (FMT) emerges as a powerful non-invasive imaging tool with the ability to resolve fluorescence signals from sources located deep in living tissues. Yet, the accuracy of FMT reconstruction depends on the deviation of the as ...
2020
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Near infrared optical tomography (NIROT) is an emerging modality that enables imaging the oxygenation of tissue, which is a biomarker of tremendous clinical relevance. Measuring in reflectance is usually required when NIROT is applied in clinical scenarios ...
2020
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In preterm infants, there is a risk of long-term cognitive, motor and behavioral impairments due to hemorrhagic and/or ischemic lesions. If detected early, lesions can be prevented. A bedside imaging modality, capable of early detection of both disorders, ...
SPRINGER INTERNATIONAL PUBLISHING AG2020
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We present the first laboratory results of the new generation of time domain near-infrared optical tomography setup, which is based on a time-of-flight 32×32 SPAD camera with high photon detection probability in the NIR range. ...
2018
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To increase the spatial resolution of near-infrared optical tomography, we successfully designed and tested a 32×32 time-resolved SPAD image sensor with unprecedented sensitivity in the near-infrared and fast image acquisition speed. ...
2018
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Oxygenation of a tumor is one of the most important predictive factors: hypoxia is associated with aggressive tumors and substantially lower survival rate. Despite this high relevance of tumor oxygenation, there is currently no bedside technique available ...
In a turbid medium such as biological tissue, near-infrared optical tomography (NIROT) can image the oxygenation, a highly relevant clinical parameter. To be an efficient diagnostic tool, NIROT has to have high spatial resolution and depth sensitivity, fas ...
Optica Publishing Group2022
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Tim-domain near-infrared optical tomography (TD NIROT) techniques based on diffuse light were gaining performance over the last years. They are capable of imaging tissue at several centimeters depth and reveal clinically relevant information, such as tissu ...
