Personne
Li Dong
Cette personne n’est plus à l’EPFL
Publications associées (7)
Lab-on-a-chip technologies for manipulation and imaging of C. elegans worms and embryos
The nematode Caenorhabditis elegans is an attractive model organism, owing notably to its short life cycle, genetic tractability, and optical transparency facilitating microscopic observation. This thesis deals with the realization of technological tools f ...
EPFL20188-Channel Single Embryo Pipette For Accurate C-Elegans Bioassays
Martinus Gijs, Thomas Lehnert, Li Dong, Jingwei Zhang
The nematode Caenorhabditis elegans (C. elegans) is a powerful model organism for addressing fundamental biological questions related to human disease and aging. Accurate control of the number of worms is a primary step for quantitative biological or bioch ...
IEEE2018An Integrated Microfluidic Device For C-Elegans Early Embryogenesis Studies And Drug Assays
Martinus Gijs, Pierre Gönczy, Thomas Lehnert, Matteo Cornaglia, Li Dong, Radek Jankele, Jingwei Zhang
The Caenorhabditis elegans embryo is a widely used model for the functional analysis of dynamic cellular processes, such as chromosome segregation, cytokinesis or lineage analysis. However, the conventional embryo preparation method that relies on manually ...
Ieee2017C. Elegans Immobilization Using Deformable Microfluidics For In Vivo Studies Of Early Embryogenesis And Intestinal Microbiota
Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong, Xiaopeng Huang, Jingwei Zhang
The genome of the nematode Caenorhabditis elegans shows far-reaching similarities to that of humans. C. elegans is therefore considered as a powerful model organism in biological research related to humans, for instance for the study of human diseases. Suc ...
Ieee2017Versatile size-dependent sorting of C-elegans nematodes and embryos using a tunable microfluidic filter structure
Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong
The roundworm Caenorhabditis elegans (C. elegans) is a powerful model organism for addressing fundamental biological questions related to human disease and aging. Its life cycle consists of an embryo stage, four larval stages that can be clearly distinguis ...
Royal Soc Chemistry2016On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites
Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong
Like other animals, C. elegans nematodes have the ability to socially interact and to communicate through exchange and sensing of small soluble signaling compounds that help them cope with complex environmental conditions. For the time being, worm biocommu ...
Royal Soc Chemistry2016Size-dependent sorting of C. elegans nematodes through an adjustable microfluidic filter structure.
Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong
We introduce a new and simple microfluidic sorting device based on adjustable filter structures that can be easily tuned by external pressure for a specific size-dependent C. elegans worm sorting experiment. A single device can be used for selecting and so ...
2016