Personne
Anna Dostalova
Cette personne n’est plus à l’EPFL
Publications associées (4)
Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach
Bruno Lemaitre, Camilla Carla Alma Ceroni, Mark Austin Hanson, Anna Dostalova
Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading microorganisms. These short, cationic peptides have been implicated in many biological processes, primarily involving innate immunity. In vitro studies have shown AMPs kill bac ...
Cambridge University Press2019The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila
Bruno Lemaitre, Anna Dostalova
Antimicrobial peptides (AMPs) are small cationic molecules best known as mediators of the innate defence against microbial infection. While in vitro and ex vivo evidence suggest AMPs' capacity to kill cancer cells, in vivo demonstration of an anti-tumour r ...
ELIFE SCIENCES PUBLICATIONS LTD2019Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps
Bruno Lemaitre, Samuel Rommelaere, Anna Dostalova
Background: Members of the thioester-containing protein (TEP) family contribute to host defence in both insects and mammals. However, their role in the immune response of Drosophila is elusive. In this study, we address the role of TEPs in Drosophila immun ...
2017Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association
Bruno Lemaitre, Anna Dostalova
Trypanosomatid parasites are significant causes of human disease and are ubiquitous in insects. Despite the importance of Drosophila melanogaster as a model of infection and immunity and a long awareness that trypanosomatid infection is common in the genus ...
American Society for Microbiology2015