Personne

Marta Jole Ildelfonsa Airaghi Leccardi

Cette personne n’est plus à l’EPFL

Publications associées (19)

Three-dimensional multilayer concentric bipolar electrodes restrict spatial activation in optic nerve stimulation

Diego Ghezzi, Eleonora Borda, Ricardo Camilo Moreira, Marta Jole Ildelfonsa Airaghi Leccardi, Vivien Gaillet, Elodie Geneviève Zollinger

Objective. Intraneural nerve interfaces often operate in a monopolar configuration with a common and distant ground electrode. This configuration leads to a wide spreading of the electric field. Therefore, this approach is suboptimal for intraneural nerve ...

IOP Publishing Ltd2022

POLYRETINA restores light responses in vivo in blind Gottingen minipigs

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Paola Vagni, Elodie Geneviève Zollinger, Charles-Henri Puncho Jérôme Vila, Golnaz Sherafatipour

Retinal prostheses hold potential for artificial vision in blind people. Here, authors show that POLYRETINA, a large and high-density photovoltaic epiretinal device, restores light-evoked cortical responses in blind Gottingen minipigs at safe irradiance le ...

NATURE PORTFOLIO2022

Photovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Naïg Aurelia Ludmilla Chenais

Retinal prostheses hold the promise of restoring vision in totally blind people. However, a decade of clinical trials highlighted quantitative limitations hampering the possibility of reaching this goal. A key challenge in retinal stimulation is to indepen ...

2021

Development of a new visual prosthesis for preclinical studies on artificial vision

Marta Jole Ildelfonsa Airaghi Leccardi

The technological evolution in materials science and microengineering favored the production of advanced visual prostheses useful for fighting blindness and to improve patients quality of life. Visual prostheses aim at replacing lost visual functions by ar ...

EPFL2020

Naturalistic spatiotemporal modulation of epiretinal stimulation increases the response persistence of retinal ganglion cell

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Naïg Aurelia Ludmilla Chenais

Objective. Retinal stimulation in blind patients evokes the sensation of discrete points of light called phosphenes, which allows them to perform visually guided tasks, such as orientation, navigation, object recognition, object manipulation and reading. H ...

2020

Photovoltaic organic interface for neuronal stimulation in the near-infrared

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Laura Ferlauto, Naïg Aurelia Ludmilla Chenais, Elodie Geneviève Zollinger

Organic materials, such as conjugated polymers, are attractive building blocks for bioelectronic interfaces. In particular, organic semiconductors show excellent performance in light-mediated excitation and silencing of neuronal cells and tissues. However, ...

2020

Capacitive-like photovoltaic epiretinal stimulation enhances and narrows the network-mediated activity of retinal ganglion cells by recruiting the lateral inhibitory network

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Naïg Aurelia Ludmilla Chenais

Photovoltaic retinal prostheses theoretically offer the possibility of a standalone high-resolution electrical stimulation of the retina. However, achieving focused epiretinal stimulation is particularly challenging, because of axonal activation and electr ...

2019

Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis

Diego Ghezzi, Kevin Sivula, Samuel Charles Antoine Gilliéron, Marta Jole Ildelfonsa Airaghi Leccardi, Laura Ferlauto, Paola Vagni, Naïg Aurelia Ludmilla Chenais, Michele Bevilacqua

Retinal prostheses have been developed to fight blindness in people affected by outer retinal layer dystrophies. To date, few hundred patients have received a retinal implant. Inspired by intraocular lenses, we have designed a foldable and photovoltaic wid ...

2018

Soft Three-dimensional self-opening intraneural peripheral interface for optic nerve stimulation

Diego Ghezzi, Eleonora Borda, Marta Jole Ildelfonsa Airaghi Leccardi

Retinitis Pigmentosa and age-related macular degeneration are two of the principal causes of blindness in industrialized countries, for which there is still no established prevention, treatment or cure. In the past decade, retinal prostheses emerged as pro ...

2018

A comprehensive study of neural retina stimulation towards better visual prosthesis resolution

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Laura Ferlauto, Naïg Aurelia Ludmilla Chenais

A major obstacle to make retinal prostheses a realistic technology to restore a functional form of vision allowing normal mobility is the low resolution achieved by current devices. Aims. Using photovoltaic pixels based on organic materials, we aimed at bu ...

2018

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