Publications de Daniel Roman Blessing

Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells

Florian Maria Wurm, Bernard Schneider, Vivianne Padrun, Nicole Déglon, Daniel Roman Blessing, Gabriel Vachey

Adeno-associated virus (AAV) vectors are currently among the most commonly applied for in vivo gene therapy approaches. The evaluation of vectors during clinical development requires the production of considerable amounts of highly pure and potent vectors. ...

2019

Validation of Scalable and Compliant AAV Production

Florian Maria Wurm, Bernard Schneider, Daniel Roman Blessing, Gabriel Vachey, Nicole Déglon

Cell Press2017

Suspension-Adapted HEK 293 Cells in Orbital Shaken Bioreactors for the Production of Adeno-Associated Virus Vectors

Florian Maria Wurm, Bernard Schneider, Daniel Roman Blessing, Nicole Déglon

Nature Publishing Group2016

Transient Production of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Therapy Applications Using Suspension-Adapted HEK 293 Cells in Orbital Shaken Bioreactors

Florian Maria Wurm, Lucia Baldi Unser, Bernard Schneider, Daniel Roman Blessing, Monique Montavon, Nicole Déglon

Nature Publishing Group2015