Riccardo Dainese

Cette personne n’est plus à l’EPFL

Publications associées (17)

À propos
Confidentialité
Mentions légales

Graph Chatbot

A Comprehensive Drosophila melanogaster Transcription Factor Interactome

Bart Deplancke, Riccardo Dainese, Jean-Daniel Feuz, Sachi Iiyama Inukai

Combinatorial interactions among transcription factors (TFs) play essential roles in generating gene expression specificity and diversity in metazoans. Using yeast 2-hybrid (Y2H) assays on nearly all sequence-specific Drosophila TFs, we identified 1,983 pr ...

2019

ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer

Didier Trono, Bart Deplancke, Julien Léonard Duc, Julie Marie Russeil, Riccardo Dainese, Marco Cassano, Michaël Imbeault, Sunil Kumar Raghav, Petra Catalina Schwalie, Suk Min Jang

Krüppel-associated box zinc finger proteins (KZFPs) constitute the largest family of mammalian transcription factors, but most remain completely uncharacterized. While initially proposed to primarily repress transposable elements, recent reports have revea ...

Nature Research2019

System for capture or immunoprecipitation of a protein-dna complex

Bart Deplancke, Riccardo Dainese

The present invention concerns a system for immunoprecipitation of a protein-DNA complex or for capture of a protein-DNA complex including: - a microfluidic device including a plurality of antibody units, wherein each antibody unit includes at least one mi ...

2019

Adaptive damage retention mechanism enables healthier yeast population

Riccardo Dainese

During cytokinesis in budding yeast (Saccharomyces cerevisiae) damaged proteins are distributed asymmetrically between the daughter and the mother cell. Retention of damaged proteins is a crucial mechanism ensuring a healthy daughter cell with full replica ...

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2019

Simplified Drop-seq workflow with minimized bead loss using a bead capture and processing microfluidic chip

Bart Deplancke, Esther Amstad, Johannes Julius Bues, Riccardo Dainese, Marjan Biocanin

Single-cell RNA-sequencing (scRNA-seq) has revolutionized biomedical research by enabling the in-depth analysis of cell-to-cell heterogeneity of tissues with unprecedented resolution. One of the catalyzing technologies is single cell droplet microfluidics, ...

2019

Device for high throughput single-cell studies

Bart Deplancke, Johannes Julius Bues, Riccardo Dainese, Marjan Biocanin

The present invention concerns a microfluidic device or chip including at least one inlet for introducing at least one object into the device; an oil inlet for introducing an oil that supports droplet formation into the device or a droplet forming substanc ...

2018

SMiLE-seq identifies binding motifs of single and dimeric transcription factors

Didier Trono, Giovanna Ambrosini, Bart Deplancke, Philipp Bucher, Romain Fernand Pietro Groux, Riccardo Dainese, Daniel Alpern, Michaël Imbeault, Alina Isakova, Pernille Yde Rainer

Resolving the DNA-binding specificities of transcription factors (TFs) is of critical value for understanding gene regulation. Here, we present a novel, semiautomated protein-DNA interaction characterization technology, selective microfluidics-based ligand ...

Nature Publishing Group2017

Page 2 sur 2