Publications de Jun Lu | EPFL Graph Search

Multimodal fusion of liquid biopsy and CT enhances differential diagnosis of early-stage lung adenocarcinoma

Jiancheng Yang, Li Zhang, Jun Lu, Hua Zhong, Yunhua Zhang

This research explores the potential of multimodal fusion for the differential diagnosis of early-stage lung adenocarcinoma (LUAD) (tumor sizes < 2 cm). It combines liquid biopsy biomarkers, specifically extracellular vesicle long RNA (evlRNA) and the comp ...

Nature Portfolio2024

Fluoride-Rich, Organic-Inorganic Gradient Interphase Enabled by Sacrificial Solvation Shells for Reversible Zinc Metal Batteries

Lei Zhang, Kangning Zhao, Jun Lu, Xu Zhang

Zinc metal batteries are strongly hindered by water corrosion, as solvated zinc ions would bring the active water molecules to the electrode/electrolyte interface constantly. Herein, we report a sacrificial solvation shell to repel active water molecules f ...

Amer Chemical Soc2023

Deep learning parametric response mapping from inspiratory chest CT scans: a new approach for small airway disease screening

Jiancheng Yang, Zhiye Wang, Jun Lu, Zhigang Li, Lin Qi, Ming Li, Bo Du, Yuxuan Sun, Ziyi Liu

Objectives Parametric response mapping (PRM) enables the evaluation of small airway disease (SAD) at the voxel level, but requires both inspiratory and expiratory chest CT scans. We hypothesize that deep learning PRM from inspiratory chest CT scans can eff ...

BMC2023

Lineage-specific transcriptional regulation of DICER by MITF in melanocytes

Friedrich Beermann, Jun Lu, Ping Chen

DICER is a central regulator of microRNA maturation. However, little is known about mechanisms regulating its expression in development or disease. While profiling miRNA expression in differentiating melanocytes, two populations were observed: some upregul ...

Elsevier2010

MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer

Douglas Hanahan, Jun Lu, Hao Zhang

While altered expression of microRNAs (miRs) in tumors has been well documented, it remains unclear how the miR transcriptome intersects neoplastic progression. By profiling the miR transcriptome we identified miR expression signatures associated with step ...

Cold Spring Harbor Laboratory Press2009