Publications de Weiliang Shen | EPFL Graph Search

An Off-the-Shelf Tissue Engineered Cartilage Composed of Optimally Sized Pellets of Cartilage Progenitor/Stem Cells

Dominique Pioletti, Weiliang Shen, Jiayun Huang

Articular cartilage focal lesion remains an intractable challenge in sports medicine, and autologous chondrocytes' implantation (ACI) is one of the most commonly utilized treatment modality for this ailment. However, the current ACI technique requires two ...

AMER CHEMICAL SOC2021

Knitted Silk-Collagen Scaffold Incorporated with Ligament Stem/Progenitor Cells Sheet for Anterior Cruciate Ligament Reconstruction and Osteoarthritis Prevention

Dominique Pioletti, Ting Zhu, Weiliang Shen, Jiayun Huang

Current surgical management of anterior cruciate ligament (ACL) rupture still remains an intractable challenge in ACL regeneration due to the weak self-healing capability of ACL. Inadequate cell numbers and vascularization within the articular cavity contr ...

2019

Activation of AKT-mTOR Signaling Directs Tenogenesis of Mesenchymal Stem Cells

Dominique Pioletti, Weiliang Shen

2018

Exogenous stromal derived factor-1 releasing silk scaffold combined with intra-articular injection of progenitor cells promotes bone-ligament-bone regeneration

Weiwei Zhang, Weiliang Shen, Jiayun Huang

2018

Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair

Dominique Pioletti, Weiliang Shen, Ting Zhu, Jiayun Huang

Rotator cuff tear is one of the most common types of shoulder injuries, often resulting in pain and physical debilitation. Allogeneic tendon-derived decellularized matrices do not have appropriate pore size and porosity to facilitate cell infiltration, whi ...

Elsevier2017

Ectopic tissue engineered ligament with silk collagen scaffold for ACL regeneration: A preliminary study

Dominique Pioletti, Wei Zhang, Weiliang Shen, Jiayun Huang

Anterior cruciate ligament (ACL) reconstruction remains a formidable clinical challenge because of the lack of vascularization and adequate cell numbers in the joint cavity. In this study, we developed a novel strategy to mimic the early stage of repair in ...

Elsevier2017