Publications de Jiande Zhou | EPFL Graph Search

Multiscale Porosity Microfluidics to Study Bacterial Transport in Heterogeneous Chemical Landscapes

Microfluidic models are proving to be powerful systems to study fundamental processes in porous media, due to their ability to replicate topologically complex environments while allowing detailed, quantitative observations at the pore scale. Yet, while por ...

Wiley2024

Breaking one into three: Surface-tension-driven droplet breakup in T-junctions

Philippe Renaud, François Gallaire, Arnaud Bertsch, Daniel Migliozzi, Yves-Marie François Ducimetière, Ludovic Pierre Gustave Keiser, Jiande Zhou

Droplet breakup is an important phenomenon in the field of microfluidics to generate daughter droplets. In this work, a novel breakup regime in the widely studied T-junction geometry is reported, where the pinch-off occurs laterally in the two outlet chann ...

AMER PHYSICAL SOC2023

Microfluidic device for sample encapsulation and method for operation thereof

Philippe Renaud, Jiande Zhou

The invention relates to a microfluidic device (3) comprising: - an inlet channel (31) having an inlet configured to be operatively connected with a droplet source (2) wherein the inlet channel (31) has a width wi and height hi; and - an outlet channel wit ...

2023

Passive and Deterministic Droplet Microfluidics for Single Object Encapsulation and Pairing

Jiande Zhou

The single-cell study, which dissects cell-cell heterogeneity from bulk populations, is of growing attention and importance in biological studies and clinical practices. At the core of the single-cell analysis is the efficient cell isolation and constructi ...

EPFL2023

High precision, high throughput generation of droplets containing single cells

Philippe Renaud, Arnaud Bertsch, Jiande Zhou

The Poisson limit is a major problem for the isolation of single cells in different single-cell technologies and applications. In droplet-based single-cell assays, a scheme that is increasingly popular, the intrinsic randomness during single-cell encapsula ...

ROYAL SOC CHEMISTRY2022