Bruno Emanuel Ferreira De Sousa Correia, Patrick Daniel Barth, Andreas Scheck, Hamed Khakzad, Alisa Khramushin, Jaume Bonet Martinez, Thomas Huber, Lei Shi
The Rosetta software for macromolecular modeling, docking and design is extensively used in laboratories worldwide. During two decades of development by a community of laboratories at more than 60 institutions, Rosetta has been continuously refactored and extended. Its advantages are its performance and interoperability between broad modeling capabilities. Here we review tools developed in the last 5 years, including over 80 methods. We discuss improvements to the score function, user interfaces and usability. Rosetta is available at . This Perspective reviews tools developed over the past five years in the macromolecular modeling, docking and design software Rosetta.
NATURE PUBLISHING GROUP2020