Publications de Ivan Furfaro | EPFL Graph Search

Optogenetic modulation of peripheral nociceptive neurons with biocompatible optoelectronic implants

Stéphanie Lacour, Bernard Schneider, Ivan Furfaro, Frédéric Pierre Gérald Michoud, Valentina Marie Paggi

Hyperexcitability of peripheral sensory neurons plays a critical role in the development and maintenance of chronic pain. Pharmacological analgesics used in clinics reduce neuronal activity. They often come with non‐negligible side effects. Optogenetic app ...

Wiley2025

High-resolution prosthetic hearing with a soft auditory brainstem implant in macaques

Stéphanie Lacour, Jocelyne Bloch, Ivan Furfaro, Florent-Valéry Coen, Alix Esther Anne Trouillet, Emilie Cornelia Maria Revol, Laurine Kolly, Florian Dylan Fallegger

Individuals with compromised cochlear nerves are ineligible for cochlear implants and instead rely on auditory brainstem implants (ABIs). Most users of ABIs experience sound awareness, which aids in lip reading, yet not speech intelligibility. Here we engi ...

2025

A soft, scalable and adaptable multi-contact cuff electrode for targeted peripheral nerve modulation

Silvestro Micera, Stéphanie Lacour, Katia Galan, Ivan Furfaro, Florian Dylan Fallegger, Valentina Marie Paggi, Olivier Didier Christian Rizzo

Background: Cuff electrodes target various nerves throughout the body, providing neuromodulation therapies for motor, sensory, or autonomic disorders. However, when using standard, thick silicone cuffs, fabricated in discrete circular sizes, complications ...

2024

Magnesium Test: Universal and Ultra-Sensitive Method for Measuring Reliability of Thin-Film-Encapsulated Bioelectronic Implants in Physiological Environment

Yves Leterrier, Stéphanie Lacour, Grégoire Courtine, Ivan Furfaro, Kangling Wu, Lei Wang, Claudia Kathe, Massimo Mariello

Next-generation bioelectronic implants require miniaturization, durability, and long-term functionality. Thin film encapsulations, prepared with inorganic or hybrid organic/inorganic designs, are essential for ensuring protection, low water permeation, ada ...

Wiley-V C H Verlag Gmbh2024

The e-Flower: A hydrogel-actuated 3D MEA for brain reserved; exclusive licensee American spheroid electrophysiology Association for the Advancement of

Stéphanie Lacour, Ivan Furfaro, Outman Akouissi

Traditional microelectrode arrays (MEAs) are limited to measuring electrophysiological activity in two dimen- Attribution creative commons sions, failing to capture the complexity of three-dimensional (3D) tissues such as neural organoids and spheroids. no ...

2024

Towards Mimicking Brain Mechanical Loads: Stretchable Microelectrode Arrays for Brain Spheroid Electrophysiology

Stéphanie Lacour, Ivan Furfaro, Laurine Kolly

Human neural spheroids, 3D cellular aggregates of neurons and glial cells, are a compelling biological model for studying neuronal communication in physiological and pathological conditions, such as neurodevelopment and traumatic brain injury (TBI), respec ...

FUNDACIO DE LA COMUNITAT VALENCIANA SCITO2024

Liquid Metal-Based Sensor Skin Enabling Haptic Perception of Softness

Stéphanie Lacour, Ivan Furfaro, Emilio Fernández Lavado, Haotian Chen

Haptic perception of softness is a unique feature of the human skin that relies on the concurrent measurements of the lateral deformation and compression of the skin during object manipulation. This is challenging to implement in robotics because of combin ...

2023

GaitSkin system: Wireless vibrotactile skin patch with gait tracker for sensorimotor conflict creation

Olaf Blanke, Stéphanie Lacour, Bruno Herbelin, Ivan Furfaro, Emilio Fernández Lavado, Haotian Chen, Selim Jean Habiby Alaoui

This paper details the development and preliminary testing of GaitSkin, a wearable haptic interface designed for generating sensorimotor conflicts during locomotion. The system leverages real-time gait tracking and a wireless vibrotactile skin patch to pro ...

IEEE2023

Wireless closed-loop optogenetics across the entire dorsoventral spinal cord in mice

Stéphanie Lacour, Grégoire Courtine, Quentin Barraud, Léonie Asboth, Ileana Ozana Jelescu, Ivan Furfaro, Kyungjin Kim, Jérôme Gandar, Frédéric Pierre Gérald Michoud, Claudia Kathe

Optoelectronic systems can exert precise control over targeted neurons and pathways throughout the brain in untethered animals, but similar technologies for the spinal cord are not well established. In the present study, we describe a system for ultrafast, ...

NATURE PORTFOLIO2022

Microscale Liquid Metal Conductors for Stretchable and Transparent Electronics

Stéphanie Lacour, Giuseppe Schiavone, Ivan Furfaro, Laurent Mirko Dejace, Haotian Chen

Integrated wearable electronics capable of transducing and transmitting biophysical information on complex and dynamic systems are attracting high interest across the consumer electronics, clinical, and research domains. Gallium and gallium-based liquid me ...

Wiley2021