Publications de Eleonora Borda

Spinal cord stimulation restores locomotion in a Parkinson's disease patient and rodents

Introduction: Dorsal column stimulation (DCS) of the spinal cord is emerging as a promising new technology to treat Parkinson's disease (PD). However, optimal stimulation settings that maximize its therapeutic effect on PD symptoms are yet to be determined ...

2025

In vivo recording of visually evoked potentials with novel full diamond ECoG implants

Diego Ghezzi, Eleonora Borda

Implantable neuroprosthetic devices such as electrocorticography (ECoG) and intracortical microelectrodes have the potential to restore neurological functions in disabled individuals. They constitute the direct interface with the body and require long term ...

2024

Conformable neural interface based on off-stoichiometry thiol-ene-epoxy thermosets

Diego Ghezzi, Eleonora Borda, Danashi Imani Medagoda, Marta Jole Ildelfonsa Airaghi Leccardi, Elodie Geneviève Zollinger

Off-stoichiometry thiol-ene-epoxy (OSTE+) thermosets show low permeability to gases and little absorption of dissolved molecules, allow direct low-temperature dry bonding without surface treatments, have a low Young's modulus, and can be manufactured via U ...

ELSEVIER SCI LTD2022

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Eleonora Borda

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

EPFL2022

Three-dimensional multilayer concentric bipolar electrodes restrict spatial activation in optic nerve stimulation

Diego Ghezzi, Eleonora Borda, Marta Jole Ildelfonsa Airaghi Leccardi, Vivien Gaillet, Elodie Geneviève Zollinger, Ricardo Camilo Moreira

Objective. Intraneural nerve interfaces often operate in a monopolar configuration with a common and distant ground electrode. This configuration leads to a wide spreading of the electric field. Therefore, this approach is suboptimal for intraneural nerve ...

IOP Publishing Ltd2022

Advances in visual prostheses: engineering and biological challenges

Diego Ghezzi, Eleonora Borda

Vision is an extraordinary sense through which we can appreciate the beauty of the world we live in, gain invaluable knowledge and communicate with others using visual expression and arts. On the contrary, blindness is a threatening medical condition disru ...

IOP Publishing Ltd2022

Three-dimensional concentric bipolar electrodes for high resolution optic nerve stimulation

Diego Ghezzi, Eleonora Borda, Marta Jole Ildelfonsa Airaghi Leccardi, Vivien Gaillet

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

A machine-learning algorithm correctly classifies cortical evoked potentials from both visual stimulation and electrical stimulation of the optic nerve

Diego Ghezzi, Eleonora Borda, Vivien Gaillet, Elodie Geneviève Zollinger

Objective. Optic nerve's intraneural stimulation is an emerging neuroprosthetic approach to provide artificial vision to totally blind patients. An open question is the possibility to evoke individual non-overlapping phosphenes via selective intraneural op ...

IOP PUBLISHING LTD2021

All-Printed Electrocorticography Array for In Vivo Neural Recordings

Diego Ghezzi, Eleonora Borda, Laura Ferlauto, Fabian Michael Lütolf, Nenad Marjanovic

Bioelectronic and neuroprosthetic interfaces rely on implanted microelectrode arrays (MEAs) to interact with the human body. Printing techniques, such as inkjet and screen printing, are attractive methods for the manufacturing of MEAs because they allow fl ...

2020