Maryse Fiche

Cette personne n’est plus à l’EPFL

Publications associées (14)

À propos
Confidentialité
Mentions légales

Publications associées (14)

The Ret receptor tyrosine kinase pathway functionally interacts with the ERalpha pathway in breast cancer

Cathrin Brisken, Maryse Fiche

A limited number of receptor tyrosine kinases (e.g., ErbB and fibroblast growth factor receptor families) have been genetically linked to breast cancer development. Here, we investigated the contribution of the Ret receptor tyrosine kinase to breast tumor ...

2008

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

Cathrin Brisken, Stéphanie Joëlle André, Maryse Fiche

INTRODUCTION: About 70% of breast cancers express oestrogen receptor alpha (ESR1/ERalpha) and are oestrogen-dependent for growth. In contrast with the highly proliferative nature of ERalpha-positive tumour cells, ERalpha-positive cells in normal breast tis ...

2007

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

Cathrin Brisken, Ayyakkannu Ayyanan, Maryse Fiche

Wnt and Notch signaling have long been established as strongly oncogenic in the mouse mammary gland. Aberrant expression of several Wnts and other components of this pathway in human breast carcinomas has been reported, but evidence for a causative role in ...

2006

Identification of molecular apocrine breast tumours by microarray analysis

Cathrin Brisken, Darlene Goldstein, Maryse Fiche

Previous microarray studies on breast cancer identified multiple tumour classes, of which the most prominent, named luminal and basal, differ in expression of the oestrogen receptor alpha gene (ER). We report here the identification of a group of breast tu ...

2005

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