Personne
Xiaoxue Li
Cette personne n’est plus à l’EPFL
Publications associées (4)
Autophagy as a Gatekeeper of Intestinal Homeostasis
The control of gut homeostasis by autophagy in the context of host-microbiota relationship remains poorly understood. In this issue of Developmental Cell, Nagai et al. (2021) show that autophagy plays a crucial role in enterocytes to prevent the mis-regula ...
CELL PRESS2021Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage
Bruno Lemaitre, Samuel Rommelaere, Xiaoxue Li
Animals require complex metabolic and physiological adaptations to maintain the function of vital organs in response to environmental stresses and infection. Here, we found that infection or injury in Drosophila induced the excretion of hemolymphatic lipid ...
2020Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation
Bruno Lemaitre, Wen Bin Chng, Xiaoxue Li
Animals rely on complex signaling network to mobilize its energy stores during starvation. We have previously shown that the sugar-responsive TGF beta/Activin pathway, activated through the TGF beta ligand Dawdle, plays a central role in shaping the post-p ...
2017Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila
Bruno Lemaitre, Jean Philippe Boquete, Jan Paul Dudzic, Sveta Chakrabarti, Xiaoxue Li, Esther Jeanne Collas
The JAK/STAT pathway is a key signaling pathway in the regulation of development and immunity in metazoans. In contrast to the multiple combinatorial JAK/STAT pathways in mammals, only one canonical JAK/STAT pathway exists in Drosophila. It is activated by ...
Public Library of Science2016