Publications de Lorenzo Cimmino

Structure of a membrane-bound menaquinol:organohalide oxidoreductase

Christof Holliger, Henning Paul-Julius Stahlberg, Julien Maillard, Dongchun Ni, Babatunde Edukpe Ekundayo, Lorenzo Cimmino

Organohalide-respiring bacteria are key organisms for the bioremediation of soils and aquifers contaminated with halogenated organic compounds. The major players in this process are respiratory reductive dehalogenases, corrinoid enzymes that use organohali ...

Nature Research2023

Characterization of the electron-accepting part of the organohalide respiration chain of Dehalobacter and Desulfitobacterium

Lorenzo Cimmino

Organohalide respiration (OHR) is a bacterial anaerobic process that use halogenated compounds, e.g. tetrachloroethene (PCE), as terminal electron acceptors. D. restrictus strain PER-K23, an obligate OHR bacterium (OHRB), and D. hafniense strain TCE1, a ba ...

EPFL2022

Characterization of the membrane protein complexes responsible for reductive dehalogenation

Christof Holliger, Julien Maillard, Lorenzo Cimmino

ELSEVIER2022

Stoichiometry of the Gene Products From the Tetrachloroethene Reductive Dehalogenase Operon pceABCT

Christof Holliger, Julien Maillard, Adrian Schmid, Lorenzo Cimmino

Organohalide respiration (OHR) is a bacterial anaerobic process that uses halogenated compounds, e.g., tetrachloroethene (PCE), as terminal electron acceptors. Our model organisms are Dehalobacter restrictus strain PER-K23, an obligate OHR bacterium (OHRB) ...

Frontiers Media SA2022

It takes two times two to tango - cryoEM structure resolution of the membrane-bound tetrachloroethene reductive dehalogenase complex

Christof Holliger, Julien Maillard, Dongchun Ni, Babatunde Edukpe Ekundayo, Lorenzo Cimmino

ELSEVIER2022

Microbial enrichment, functional characterization and isolation from a cold seep yield piezotolerant obligate hydrocarbon degraders

Lorenzo Cimmino

Deep-sea environments can become contaminated with petroleum hydrocarbons. The effects of hydrostatic pressure (HP) in the deep sea on microbial oil degradation are poorly understood. Here, we performed long-term enrichments (100 days) from a natural cold ...

OXFORD UNIV PRESS2020