Personne
Mathilde Stéphanie Willemin
Publications associées (20)
Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms
Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Florence Armand
IntroductionDesulfitobacterium hafniense was isolated for its ability to use organohalogens as terminal electron acceptors via organohalide respiration (OHR). In contrast to obligate OHR bacteria, Desulfitobacterium spp. show a highly versatile energy meta ...
FRONTIERS MEDIA SA2023Organohalide respiration in Firmicutes: energy metabolism and transcription regulation
Organohalides are a class of compounds often considered as persistent pollutants and harmful to environmental and human health. Some bacteria, among which are representatives from the Firmicutes phylum, are capable of using these compounds as terminal acce ...
EPFL2021Organohalide respiration: variations on a common theme
Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin, Lorenzo Cimmino
Organohalide respiration (OHR) is a bacterial anaerobic respiratory metabolism that makes use of halogenated organic compounds as terminal electron acceptors. While organohalogens have been initially thought to be mainly from anthropogenic origin, thousand ...
2021Conditional essentiality of a complex I-like enzyme in strict anaerobes: the case of Desulfitobacterium
Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Florence Armand
Respiratory complex I is a well-known player in aerobic respiration; it couples the transfer of two electrons from NADH to ubiquinone alongside with proton pumping. Bacterial complex I is usually composed of fourteen subunits forming three different module ...
2021Complex I-like enzymes in organohalide-respiring bacteria
Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Florence Armand
Complex I (NADH:ubiquinone oxidoreductase, NUO) and complex I-like enzymes have been detected in several organohalide-respiring bacteria at genomic and proteomic levels. The question of the involvement of these enzymes in organohalide respiration remains t ...
2021Hybrid Transcriptional Regulators for the Screening of Target DNA Motifs in Organohalide-Respiring Bacteria
Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin, Marie Vingerhoets
The bioremediation of persistent organohalide molecules under anoxic conditions mostly relies on the bacterial process called organohalide respiration (OHR). Organohalide-respiring bacteria (OHRB) are phylogenetically diverse anaerobic bacteria that share ...
2020Regulation of organohalide respiration
Julien Maillard, Mathilde Stéphanie Willemin
Organohalide respiration (OHR) is an anaerobic metabolism by which bacteria conserve energy with the use of halogenated compounds as terminal electron acceptors. Genes involved in OHR are organized in reductive dehalogenase (rdh) gene clusters and can be f ...
Academic Press2019RDHK Family, Regulators dedicated to Organohalide Respiration - Sequence Diversity and Functional Prediction
Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin
Organohalide respiration (OHR) is an anaerobic metabolism by which bacteria conserve energy from the use of organohalide molecules as terminal electron acceptors. Because most organohalides of anthropogenic origin are persistent pollutants, the study of ba ...
2019RDHK Family, Regulators dedicated to Organohalide Respiration - Sequence Diversity and Functional Prediction
Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin
Organohalide respiration (OHR) is an anaerobic metabolism by which bacteria conserve energy from the use of organohalide molecules as terminal electron acceptors. Because most organohalides of anthropogenic origin are persistent pollutants, the study of ba ...
2019Involvement of respiratory complex I in organohalide respiration?
Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin
Abstract Background The NADH:ubiquinone oxidoreductase (Nuo) is an assembly of proteins also known as complex I. It is the entry point for highly energetic electrons in the classical aerobic respiration process as it couples the transfer of two electrons f ...
2019