Publications de Guang Li | EPFL Graph Search

Enantioselective Total Synthesis of (+)-Stephadiamine

Qian Wang, Jieping Zhu, Baochao Yang, Guang Li

An asymmetric synthesis of (+)-stephadiamine has been accomplished featuring (a) an enantioselective dearomatizative Michael addition to generate a quaternary stereocenter; (b) a domino sequence involving reductive generation of nitrone from γ-nitro ketone ...

2023

Wind Tunnel Studies on the Prevention of Particle Accumulation Onto the Bogie of High-Speed Train

Guang Li

When high-speed train runs in the environment with a large number of airborne particles, these particles may accumulate on the bogie of the train, which will further challenge the normal operation of the bogie and reduce the riding comfort and train safety ...

2022

Application of superstatistical analysis on fluctuant surface shear in particle-laden turbulence boundary layer

Guang Li

We report on an application of superstatistics to particle-laden turbulent flow. Four flush-mounted hot-film wall shear sensors were used to record the fluctuations of the wall shear stress in sand-laden flow. By comparing the scaling exponent in sand-free ...

SPRINGER2022

Wind-tunnel experimental studies of the spatial snow distribution over grass and bush surfaces

Guang Li

The snow is one of the most important water resources in grassland in northern and western China, while the wind blowing snow due to the strong wind there is a common phenomenon, which can lead to heavy disasters to harm the local animal husbandry and tran ...

SPRINGER2022

Idealized Study of a Static Electrical Field on Charged Saltating Snow Particles

Michael Lehning, Hongxiang Yu, Guang Li

Strong electric fields, with values of tens kV/m near the surface, are observed during drifting and blowing snow events. Charge separation can significantly affect particle motion. Although several investigations attempted to shed light on the mechanisms o ...

FRONTIERS MEDIA SA2022

Enantioselective Total Synthesis of (+)-Alstilobanine C, (+)-Undulifoline, and (-)-Alpneumine H

Qian Wang, Jieping Zhu, Cyril Piemontesi, Guang Li, Nicolas David Gaeng

We report herein the enantioselective total synthesis of three monoterpene indole alkaloids, namely, (+)-alstilobanine C, (+)-undulifoline, and (-)-alpneumine H. The key features of our synthesis include: a) introduction of chirality via enantioselective d ...

Wiley-VCH Verlag GmbH2021

Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

Qian Wang, Jieping Zhu, Guang Li

Elegant asymmetric synthesis of hasubanan alkaloids have been developed over the past decades. However, a divergent approach leading to all three sub-classes of this family of natural products remains unknown. We report herein the realization of such an en ...

Nature Research2021

Mountain snow: The source of the mother river—Study of multi-scale and multi-physical process of spatio-temporal evolution of snow distribution

Guang Li

Snow is one of the most active elements on the earth, which is an important mass source of polar ice sheets and alpine glaciers, as well as a main supply for the runoff. Its distribution and evolution have a great impact on global hydrological cycle, ecosy ...

2020

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

Qian Wang, Jieping Zhu, Cyril Piemontesi, Guang Li

Controlling the cis C20/C21 relative stereochemistry remains an unsolved issue in the synthesis of eburnane-type indole alkaloids. Provided herein is a simple solution to this problem by developing a unified and diastereoselective synthesis of four represe ...

Wiley-VCH Verlag GmbH2019

FCC Physics Opportunities: Future Circular Collider Conceptual Design Report Volume 1

Pierluigi Bruzzone, Jan Steggemann, Elena Graverini, Jean-Michel Sallese, Thomas Rizzo, Luca Rossi, Rui Ning Wang, Fabio Avino, Xavier Buffat, Tatiana Pieloni

We review the physics opportunities of the Future Circular Collider, covering its e(+)e(-), pp, ep and heavy ion programmes. We describe the measurement capabilities of each FCC component, addressing the study of electroweak, Higgs and strong interactions, ...

2019