Publications de Vasiliki Bikia

Testing an inverse modeling approach with gradient boosting regression for stroke volume estimation using patient thermodilution data

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia

Stroke volume (SV) is a major indicator of cardiovascular function, providing essential information about heart performance and blood flow adequacy. Accurate SV measurement is particularly important for assessing patients with heart failure, managing patie ...

FRONTIERS MEDIA SA2025

Evaluation of a novel compliance-matching aortic graft in a swine model

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia

The mismatch of elastic properties between the arterial tissue and the vascular grafts, commonly called compliance mismatch, is responsible for many deleterious post-operative complications. Currently, there is an absence of prostheses that conform with th ...

2025

Developing Technologies to Assess Vascular Ageing: a Roadmap From Vascagenet

Vasiliki Bikia

Vascular ageing (vascular ageing) is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with poten ...

IOP Publishing Ltd2024

Novel theory and potential applications of central diastolic pressure decay time constant

Nikolaos Stergiopoulos, Georgios Rovas, Sokratis Anagnostopoulos, Vasiliki Bikia, Patrick Segers

Central aortic diastolic pressure decay time constant ( ) is according to the two-element Windkessel model equal to the product of total peripheral resistance (R) times total arterial compliance (C ). As such, it is related to arterial stiffness, which has ...

2024

Apparatus for non-invasively computing cardio-vasculature parameters using morphology of uncalibrated pressure wave signal

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia

Systems and apparatus are provided for using a non-invasively monitored uncalibrated pressure signal from a patient to compute cardiac output and other cardio-vascular parameters, thereby providing safe, effective, reliable and low cost monitoring of patie ...

2024

Method and apparatus for non-invasively computing cardio-vasculature parameters using morphology of uncorrelated pressure wave signal

Nikolaos Stergiopoulos, Vasiliki Bikia

[0054] Methods are provided for estimating key reliably and accurately predicting cardiac output using a limited set of non-invasively monitored physiologic inputs, and a calibrated one- dimensional arterial tree model, a database of synthetic data generat ...

2024

In Silico Validation of Non-Invasive Arterial Compliance Estimation and Potential Determinants of its Variability

Nikolaos Stergiopoulos, Vasiliki Bikia

Arterial compliance (AC) is an important cardiovascular parameter characterizing mechanical properties of arteries. AC is significantly influenced by arterial wall structure and vasomotion, and it markedly influences cardiac load. A new method, based on a ...

2024

On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

Nikolaos Stergiopoulos, Georgios Rovas, Sokratis Anagnostopoulos, Vasiliki Bikia

Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

Nature Portfolio2023

Design and computational optimization of compliance-matching aortic grafts

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia

Introduction: Synthetic vascular grafts have been widely used in clinical practice for aortic replacement surgery. Despite their high rates of surgical success, they remain significantly less compliant than the native aorta, resulting in a phenomenon calle ...

FRONTIERS MEDIA SA2023

Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet

Vasiliki Bikia, Patrick Segers

Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review th ...

AMER PHYSIOLOGICAL SOC2023