Publications de Barney Frederick Drake

Controlled Sensing of User-Defined Aptamer-Based Targets Using Scanning Ionic Conductance Spectroscopy

Aleksandra Radenovic, Georg Fantner, Lely Feletti, Marcos Penedo Garcia, Wayne Yang Wen Wei, Barney Frederick Drake, Helena Miljkovic, Zahra Ayar Dulabi

Solid-state nanopores offer the possibility of detecting disease biomarkers in early diagnostic applications. Standard approaches harness fingerprinting, where protein targets are bound to DNA carriers and detected in free translocation with a solid-state ...

2025

Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds

Aleksandra Radenovic, Georg Fantner, Barney Frederick Drake, Helena Miljkovic, Simon Finn Mayer, Sanjin Marion, Vytautas Navikas, Samuel Mendes Leitão

In current nanopore-based label-free single-molecule sensing technologies, stochastic processes influence the selection of translocating molecule, translocation rate and translocation velocity. As a result, single-molecule translocations are challenging to ...

2023

Time-Resolved Scanning Ion Conductance Microscopy for Three-Dimensional Tracking of Nanoscale Cell Surface Dynamics

Aleksandra Radenovic, Georg Fantner, Daniel Constam, Alexandre Louis André Persat, Barney Frederick Drake, Adrian Pascal Nievergelt, Vytautas Navikas, Samuel Mendes Leitão, Xavier Jean-Yves Pierrat, Charlène Cécile Geneviève Brillard

Nanocharacterization plays a vital role in understanding the complex nanoscale organization of cells and organelles. Understanding cellular function requires high-resolution information about how the cellular structures evolve over time. A number of techni ...

AMER CHEMICAL SOC2021

Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy

Aleksandra Radenovic, Georg Fantner, Barney Frederick Drake, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Samuel Mendes Leitão, Kristin Stefanie Grussmayer

High-resolution live-cell imaging is necessary to study complex biological phenomena. Modern fluorescence microscopy methods are increasingly combined with complementary, label-free techniques to put the fluorescence information into the cellular context. ...

Nature Research2021

Growing a 'cosmic beast': observations and simulations of MACS J0717.5+3745

Jean-Paul Richard Kneib, David Richard Harvey, Barney Frederick Drake, Mathilde Jauzac, Matthieu Schaller, Matthew Aaron Robertson, Elena Cristina Dalla Vecchia, Richard Massey

We present a gravitational lensing and X-ray analysis of a massive galaxy cluster and its surroundings. The core of MACS J0717.5+3745 (M(R < 1Mpc) similar to 2 x 10(15) M-circle dot, z = 0.54) is already known to contain four merging components. We show th ...

OXFORD UNIV PRESS2018