Publications de Rémy Marc M Gardier

Lymph node microstructure imaging using diffusion MRI: From simulations to acquisitions

Early tumor detection is crucial for maximizing treatment effectiveness and the chances of recovery. Currently, medical doctors rely on the combination of non-specific (X-ray, MRI, CT) or invasive (PET) imaging modalities and the analysis of tissue samples ...

EPFL2024

Comparing Steam and PGSE Diffusion MRI Signal of RAT Lymph Nodes Using In-Silico Simulations

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, Elda Fischi Gomez, Juan Luis Villarreal Haro, Rémy Marc M Gardier

Diffusion magnetic resonance imaging (dMRI) has demonstrated great capabilities to quantify tissue microstructure using biophysical diffusion models. Over the years, various gradient sequences have been proposed to provide sensitivity and specificity to va ...

IEEE Computer Society2024

Cellular EXchange Imaging (CEXI): Evaluation of a diffusion model including water exchange in cells using numerical phantoms of permeable spheres

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, Jonathan Rafael Patino Lopez, Ileana Ozana Jelescu, Juan Luis Villarreal Haro, Rémy Marc M Gardier

Purpose Biophysical models of diffusion MRI have been developed to characterize microstructure in various tissues, but existing models are not suitable for tissue composed of permeable spherical cells. In this study we introduce Cellular Exchange Imaging ( ...

Wiley2023

Molecular Imaging with Aquaporin-Based Reporter Genes: Quantitative Considerations from Monte Carlo Diffusion Simulations

Jean-Philippe Thiran, Jonathan Rafael Patino Lopez, Rémy Marc M Gardier

Aquaporins provide a unique approach for imaging genetic activity in deep tissues by increasing the rate of cellular water diffusion, which generates a magnetic resonance contrast. However, distinguishing aquaporin signals from the tissue background is cha ...

Amer Chemical Soc2023

Computer vision-based algorithm to sUppoRt coRrect electrode placemeNT (CURRENT) for home-based electric non-invasive brain stimulation

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Takuya Morishita, Roser Vinals Terres, Fabienne Windel, Rémy Marc M Gardier

Objective: Home-based non-invasive brain stimulation (NIBS) has been suggested as an adjunct treatment strategy for neuro-psychiatric disorders. There are currently no available solutions to direct and monitor correct placement of the stimulation electrode ...

2023

Microstructure estimation from diffusion-MRI: Compartmentalized models in permeable cellular tissue

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, Jonathan Rafael Patino Lopez, Juan Luis Villarreal Haro, Rémy Marc M Gardier

Diffusion-weighted magnetic resonance imaging (DW-MRI) is used to characterize brain tissue microstructure employing tissue-specific biophysical models. A current limitation, however, is that most of the proposed models are based on the assumption of negli ...

2022

Examining the synergistic effects of a cognitive control video game and a home-based, self-administered non-invasive brain stimulation on alleviating depression: the DiSCoVeR trial protocol

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Takuya Morishita, Roser Vinals Terres, Fabienne Windel, Rémy Marc M Gardier

Enhanced behavioral interventions are gaining increasing interest as innovative treatment strategies for major depressive disorder (MDD). In this study protocol, we propose to examine the synergistic effects of a self-administered home-treatment, encompass ...

SPRINGER HEIDELBERG2022