Publications de Ali Ghasemi | EPFL Graph Search

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Dendritic cells (DCs) are specialized myeloid cells with the ability to uptake, process, and present antigens to T lymphocytes. They also generate cytokine and chemokine gradients that regulate immune cell trafficking, activation, and function. Monocyte-de ...

EPFL2024

CYTOKINE-ARMORED DENDRITIC CELL PROGENITORS SYNERGIZE WITH CAR-T CELLS IN SOLID TUMORS

Michele De Palma, Ali Ghasemi, Amaia Martinez Usatorre

Mary Ann Liebert, Inc2023

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Michele De Palma, Nahal Mansouri, Ali Ghasemi, Bruno Torchia, Yahya Mohammadzadeh, Alan Nicolas Thierry Guichard

Dendritic cells (DCs) are antigen-presenting myeloid cells that regulate T cell activation, trafficking and function. Monocyte-derived DCs pulsed with tumor antigens have been tested extensively for therapeutic vaccination in cancer, with mixed clinical re ...

Nature Portfolio2023

Engineered progenitor cells and methods of use

Michele De Palma, Ali Ghasemi, Amaia Martinez Usatorre

Disclosed herein are engineered progenitor cells and methods of using the same. Also disclosed herein are engineered cells differentiated from engineered progenitor cells of the present disclosure. Also disclosed herein are methods of treating a condition ...

2023

Partial Discharge Localization Using Electromagnetic Time Reversal: A Performance Analysis

Marcos Rubinstein, Hamidreza Karami, Mohammad Azadifar, Zhaoyang Wang, Ali Ghasemi

In this study, first, a comparison on the application of electromagnetic time reversal (EMTR) and time difference of arrival (TDoA) in partial discharge localization in power transformers is presented. A two-dimensional finite-difference time-domain simula ...

2020

Tweaking DNA of myeloid cells curbs cancer spread

Michele De Palma, Ali Ghasemi

Blood cells called myeloid cells can facilitate metastasis - the spread of a tumour to distant organs. Taming these cells with drugs that alter the chemical structure of their DNA limits metastasis in mice. ...

NATURE PUBLISHING GROUP2020