Publications de Gloria Porro | EPFL Graph Search

Electrokinetic microdevices for biological sample processing

Carlotta Guiducci, Pierre-Emmanuel Marie Thiriet, Gloria Porro

Microsystems combining fluid dynamics and electric-field-induced forces have emerged as powerful tools for manipulating and isolating biological species. Advances in electrokinetic theory, combined with optimized microfabrication processes, are at the core ...

Springer Science and Business Media LLC2024

Combining Hydrodynamic and Electrokinetic Forces for Particle Manipulation in Bioanalytical Microsystems

Gloria Porro

This Thesis introduces technologies for particle manipulation in bioanalytics, designed to advance integrative biology leveraging biomarker quantification. Bioanalytical information is essential for uncovering mechanisms and pathways, particularly in nonco ...

EPFL2024

MarrowCellDLD: a microfluidic method for label-free retrieval of fragile bone marrow-derived cells

Carlotta Guiducci, Gloria Porro

Functional bone marrow studies have focused primarily on hematopoietic progenitors, leaving limited knowledge about other fragile populations, such as bone marrow adipocytes (BMAds) and megakaryocytes. The isolation of these cells is challenging due to rup ...

Nature Portfolio2023

Particle-sorting fluidic device and methods for using thereof

Carlotta Guiducci, Gloria Porro, Kevin Keim

Device, system and method for sorting particles comprised into a fluid are disclosed that improve the current settings of deterministic lateral displacement (DLD)-based microfluidic devices, so to sort and detect small particles such as extracellular vesic ...

2022

Device and method for pre-term birth risk assessment

Carlotta Guiducci, Erick Antonio Garcia Cordero, David Baud, Gloria Porro

The invention relates to a vaginal fluid monitoring device embedded into a feminine sanitary pad, said device comprising a stack of the following elements: An absorbent layer (100) configured to be in proximity to, and collect, a vaginal fluid; and A biose ...

2021

Rapid Multianalyte Microfluidic Homogeneous Immunoassay on Electrokinetically Driven Beads

Carlotta Guiducci, Pierre-Emmanuel Marie Thiriet, Gloria Porro, Danashi Imani Medagoda

The simplicity of homogeneous immunoassays makes them suitable for diagnostics of acute conditions. Indeed, the absence of washing steps reduces the binding reaction duration and favors a rapid and compact device, a critical asset for patients experiencing ...

2020